Neuroblastoma (NB) is the most common solid tumor in pediatric cases. NB accounts for about 8% of malignancies patients younger than 15 years, and since 50% newly diagnosed cases metastasize to regional lymph nodes, bone marrow, bone, liver, skin, disease usually its late stages. Overexpression N-MYC, which characterized by poor prognosis NB, changes progression course treatment. Targeting thes...