نتایج جستجو برای: targeted delivery

تعداد نتایج: 344312  

2012
Vinod Kumar Khanna

The role of targeting of the diseased region by a drug is emphasized. The rationale for resorting to nanomaterials as drug carriers is explained. A clear understanding of the biological environment, its degradation in diseased condition, and the interaction of the drug with it in normal condition and during illness lie at the core of successful drug delivery. Passive and active drug targeting a...

2014
Brian C Wengerter Joseph A Katakowski Jacob M Rosenberg Chae Gyu Park Steven C Almo Deborah Palliser Matthew Levy

Effective therapeutic vaccines often require activation of T cell-mediated immunity. Robust T cell activation, including CD8 T cell responses, can be achieved using antibodies or antibody fragments to direct antigens of interest to professional antigen presenting cells. This approach represents an important advance in enhancing vaccine efficacy. Nucleic acid aptamers present a promising alterna...

Journal: : 2021

Neuroblastoma (NB) is the most common solid tumor in pediatric cases. NB accounts for about 8% of malignancies patients younger than 15 years, and since 50% newly diagnosed cases metastasize to regional lymph nodes, bone marrow, bone, liver, skin, disease usually its late stages. Overexpression N-MYC, which characterized by poor prognosis NB, changes progression course treatment. Targeting thes...

Journal: :Acta Pharmaceutica Sinica B 2014

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