نتایج جستجو برای: target site insensitivity
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Ethylene responses in Arabidopsis are mediated by a small family of receptors, including the ETR1 gene product. Specific mutations in the N-terminal ethylene-binding domain of any family member lead to dominant ethylene insensitivity. To investigate the mechanism of ethylene insensitivity, we examined the effects of mutations on the ethylene-binding activity of the ETR1 protein expressed in yea...
introduction: complete androgen insensitivity syndrome (previously called testicular feminization) is specified by a 46 xy karyotype and negative sex chromatin, bilateral undescended testes, female genitalia appearance, and lack of mullerian derivatives. discussion: our medline search revealed that this is the first reported case of bilateral sertoli–leydig cell tumor (slct) in androgen insensi...
Prediction of Target Genes and Pathways Associated With Cetuximab Insensitivity in Colorectal Cancer
Target-site and non-target-site resistance mechanisms to ALS inhibiting herbicides in Papaver rhoeas
با توجه به حیاتی بودن نقش آنزیم topo ii در چرخه سلولی، این آنزیم میتواند هدف درمانی مهمی در شیمی درمانی سرطان باشد. فلوروکینولون ها به عنوان مهارکننده های آنزیم توپوایزومراز (ژیراز) باکتری به خوبی شناخته شده اند و اخیرا نیز نشان داده شده است که توان مهار توپوایزومراز ii یوکاریوتیکها را هم دارند. در این راستا در این پایان نامه ترکیبات جدیدی از فلوروکینولونها به منظور مهار آنزیم توپوایزومراز انسا...
Five BC₁ lines and 16 house fly mass-cross homozygous lines were generated from crosses of the pyrethroid resistant ALHF (wild-type) and susceptible aabys (bearing recessive morphological markers on each of five autosomes) strains. Each of the resulting homozygous lines had different combinations of autosomes from the resistant ALHF strain. Levels of resistance to permethrin were measured for e...
NMDA receptors are typically excited by a combination of glutamate and glycine. Here we describe excitatory responses in CNS myelin that are gated by a glycine agonist alone and mediated by NR1/NR3 "NMDA" receptor subunits. Response properties include activation by d-serine, inhibition by the glycine-site antagonist CNQX, and insensitivity to the glutamate-site antagonist d-APV. d-Serine respon...
how to cite this article: karimi m, fallah r. a case report of congenital insensitivity to pain and anhidrosis (cipa). iran j child neurol 2012; 6(3): 45-48. congenital insensitivity to pain and anhidrosis (cipa) or hereditary sensoryautonomic neuropathies type iv (hsan type iv) is an extremely rare autosomalrecessive disorder initially described by swanson in 1963.we report a 2.5-year-old bo...
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