This paper shows that the Poisson multi-Bernoulli mixture (PMBM) density is a multi-target conjugate prior for general target-generated measurement distributions and arbitrary clutter distributions. That is, this model standard dynamic with birth model, predicted filtering densities are PMBMs. We derive corresponding PMBM recursion. Based on result, we implement filter point-target models negat...

Photodynamic therapy has been applied quite extensively over the last few years, whereby the activation of photosensitizers by light causes the production of reactive oxygen species such as singlet oxygen, which is cytotoxic. The goal of this study was the enhancement of the photodynamic activity of photosensitizers through their delivery to specific, sensitive intracellular compartments of tar...

Multiple target tracking (MTT) denotes the process of estimating the set of target trajectories based on a sequence of noise-corrupted measurements including missed detections and false alarms. Nowadays, MTT has found applications in numerous areas, such as air traffic control, autonomous vehicles and robotics, computer vision and biomedical research. In recent years, a significant research tre...

Peptide nucleic acids (PNAs) are very attractive antisense and antigene agents, but these molecules are not passively taken into cells. Here, using a functional cell assay and fluorescent-based methods, we investigated cell uptake and antisense activity of a tridecamer PNA that targets the HIV-1 polypurine tract sequence delivered using the arginine-rich (R/W)9 peptide (RRWWRRWRR). At micromola...

(2013) Robust, specific ratiometric biosensing using a copper-free clicked quantum dot-DNA aptamer sensor. 5 We report herein the successful preparation of a compact, functional CdSe/ZnS core/shell quantum dot (QD)-DNA conjugate via the highly efficient copper-free " click chemistry " (CFCC) between a dihydro-lipoic acid-polyethylene glycol-azide (DHLA-PEG-N 3) capped QD and a cyclooctyne modif...

Background: Polysaccharides have long been used as immune-modulators in various pathologic conditions including inflammation and solid malignancies. Objective: To evaluate the effects of Zymosan and Betaglucan on cytotoxic reactions in an effectortarget conjugate system. Methods: Blood was obtained from 20 healthy subjects; purified mononuclear leukocytes (monocytes and lymphocytes) were extrac...