Twenty-five infants with transient tachypnoea of the newborn (TTN) were examined by serial echocardiography during the first 4 days of life. The infants could be divided clinically into two groups: group 1 (n = 19) babies with mild classical TTN requiring less than 40% oxygen, and group 2 (n = 6) babies with severe TTN needing greater than 60% oxygen. Apart from amount of oxygen these two group...

‘Hippocrates’ the father of modern medicine; characterized ‘pleuritis’ by some demarcating features such as chest pain, fever, chills with shivering, dry cough associated breathing difficulties orthopnoea & tachypnoea. Pleuritis can be differentiated into its marked tributaries like sanguineous, bilious, which is a subject to well precised diagnosis avoid forthcoming execrable complications ple...

Typical symptoms: breathlessness, fatigue, ankle swelling. Typical signs: tachycardia, tachypnoea, pulmonary rales, pleural effusion, raised jugular venous pressure (JVP), peripheral oedema, hepatomegaly. Objective evidence of a structural or functional abnormality of the heart at rest: cardiomegaly, third heart sound, cardiac murmurs, echocardiogram abnormalities, raised natriuretic peptide co...

Background: Chronic interstitial lung diseases in children (chILD) are a heterogeneous group of disorders that can represent a clinical challenge for pediatric pneumologists. Among them, neuroendocrine cell hyperplasia of infancy (NEHI) is a diffuse lung disease prevalent in the first years of life that spontaneously improves over time. The clinical presentation of NEHI is indistinguishable fro...

An infant presented with failure to thrive, tachypnoea, and hypoxia reversed by oxygen. Lung function showed decreased pulmonary compliance; lung biopsy showed desquamative interstitial pneumonitis. Chloroquine 10 mg/kg/day resulted in improvement and relapse when temporarily stopped. The patient was completely asymptomatic during four years' treatment and six months after stopping treatment.

An infant infected with HIV presented with fever, tachypnoea, hypoxia, and radiological evidence of bilateral pneumonitis. Fluorescent antibody technique identified Pneumocystis carinii within 24 hours from secretions obtained by nasopharyngeal aspiration. This rapid, non-invasive method should be the first line investigation of suspected P carinii pneumonia in immunocompromised patients.

We have used a novel neurophysiological technique in the NeuroScope system in combination with conventional electroencephalography (EEG) to monitor both brainstem and cortical activity simultaneously in real-time in a girl with Rett syndrome. The presenting clinical features in our patient were severe sleep disturbances, irregular breathing in the awake state dominated by Valsalva's type of bre...

Our aim was to assess the impact of motor activity and of arousing stimuli on respiratory rate in the awake rats. The study was performed in male adult Sprague-Dawley (SD, n=5) and Hooded Wistar (HW, n=5) rats instrumented for ECG telemetry. Respiratory rate was recorded using whole-body plethysmograph, with a piezoelectric sensor attached for the simultaneous assessment of motor activity. All ...