INTRODUCTION Left ventricular free wall rupture (LVFWR) is a frequent cause of death after acute myocardial infarction, and its repair remains a surgical challenge. CASE PRESENTATION TachoSil(®) is a ready-to-use equine collagen patch which has been successfully used for hemostasis in cardiovascular surgery. However, a limited number of studies have reported its application for LVFWR repair. ...

Objective: To compare between electrocautery and fibrin sealant hemostasis in rats after partial hepatectomy. Methods: we used 24 Wistar rats, which were submitted to 30% hepatic resection, divided into two groups of 12 animals each: Group Electrocautery and Group Tachosil®. These animals were evaluated after three and 14 days. We assessed the presence of complications, laboratory tests and his...

Local hemostyptic agents are of great value to significantly reduce bleeding complications and various devices have become available for clinical use. The aim of this multicenter postauthorization surveillance was to study the surgeons' expectations regarding efficacy and safety of the surgical patch coated with human coagulation factors (TachoSil) under routine clinical conditions. A total of ...

Abstract Introduction A penile tunica defect may arise during prosthesis surgery or reconstruction of the penis in patients with Peyronie’s disease. Collagen fleece (TachoSil) was recently reported to cover clinical success. However, it is not known what histological outcomes these grafts are penis. Objective We study novel application TachoSil graft an experimental animal model. looked at rege...

Background. Despite progress in surgical techniques applied during hepatobiliary and pancreas (HPB) surgery, bleeding and bile leak remain significant contributors to postoperative mortality and morbidity. Topical hemostatics have been developed and utilized across surgical specialties, but data regarding effectiveness remains inconsistent and sparse in HPB surgery. Methods. A comprehensive sea...

introduction left ventricular free wall rupture (lvfwr) is a frequent cause of death after acute myocardial infarction, and its repair remains a surgical challenge. conclusions a hemodynamic study was acceptable at a 12-month follow-up, and no complication was seen. case presentation tachosil® is a ready-to-use equine collagen patch which has been successfully used for hemostasis in cardiovascu...

BACKGROUND Surgery of locally advanced and/or recurrent rectal cancer can be complemented with intra-operative electron radiation therapy (IOERT) to deliver a single dose of radiation directly to the unresectable margins, while sparing nearby sensitive organs/structures. Haemorrhages may occur and can affect the dose distribution, leading to an incorrect target irradiation. The TachoSil (TS) su...

Intestinal anastomotic leaking, which involves the discharge of chemically aggressive, non-sterile fluids into abdomen, remains one most dreaded postoperative complications abdominal surgery. Depending on site and patient condition, incidence ranging between 4% 21% mortality rates up to 27% are reported. Currently available surgical sealants only poorly address issue, especially since commonly ...

CLINICAL CASE We report 2 cases of patients affected by non-infectious corneal macroperforations treated with TachoSil(®) and Tutopach(®), which closed the defect. DISCUSSION This procedure is an excellent choice for the emergency treatment of corneal perforation, especially in those centres that have no other therapeutic options, preserving the eye and visual acuity.