A 28 year old woman with Hashimoto's disease was treated with desiccated thyroid and triiodothyronine (T3). She improved steadily during the first 2 to 3 months and thyroidal function tests turned to normal. Then, in spite of continuing treatment, her serum T4 level decreased gradually and she became fatigued. A serum T3 radioimmunoassay manifested an interference pattern suggested anti-T3 anti...

We studied the effects of cortisol and triiodothyronine (T3) on 20-day fetal rat lung cell cultures. Cortisol enhanced the production of surfactant-associated saturated phosphatidylcholine while T3 did not. However, T3 potentiated the cortisol effect. We observed that T3 enhanced the response of cultures enriched with alveolar type H cells to fibroblast-pneumonocyte factor (FPF). Intracellular ...

BACKGROUND The concentration of triiodothyronine (T3) in human serum is extremely low and can be determined only by very sensitive methods. We developed a homogeneous enzyme immunoassay for T3 analysis in unextracted serum. METHODS A T(3) derivative was conjugated to the -SH groups of glycogen phosphorylase b (GPb) from rabbit muscle. Conjugation caused inhibition of enzyme activity, and the ...

BACKGROUND It is well known that certain non-thyroidal critical illness may lead to euthyroid sick syndrome(ESS). There are little reports about the change of thyroid hormone in the children's central nervous system (CNS) infections. RESULTS The results of serum TT3, TT4 and TSH in these children were compared with those in 20 cases of healthy adults and 20 cases of adults with primary hypoth...

A field experiment was conducted to study the effect of iron fertilization on growth, yield and quality groundnut (Arachis hypogaea L.) during kharif, 2016 (June September at instructional farm, Swami Keshwanand Rajasthan Agricultural University, Bikaner, Rajasthan, India. Twelve treatments viz. T1: control (water spray); T2: FeSO4 basal @ 25 kg ha-1; T3: Foliar spray citric acid 0.1% 45 75 day...

Effects of triiodothyronine (T3) on the expression of cytoskeletal and myofibrillar proteins in adult rat cardiomyocytes (ARC) were followed during two weeks of culture in the presence of 20% T3-depleted (stripped) FCS. Control cultures expressed mainly b -myosin heavy chain (MHC) mRNA. T3 caused a switch to a -MHC expression and a dose-dependent increase of a -smooth muscle ( a -sm) actin mRNA...

Thyroid Hormones (TH) act on multiple metabolic process influencing the concentration and activity of numerous enzymes, the metabolism of substrates, vitamins and minerals, and the response of target tissues to several hormones. These TH have critical roles in cell differentiation, growth, and regulation of oxygen consumption and thermogenesis [1]. Thyroid disease occurs when the gland is enlar...

BACKGROUND/AIMS Vascular relaxation caused by Triiodothyronine (T3) involves direct activation of endothelial cells (EC) and vascular smooth muscle cells (VSMC). Activation of protein kinase G (PKG) has risen as a novel contributor to the vasorelaxation mechanism triggered by numerous stimuli. We hypothesize that T3-induced vasorelaxation involves PKG/vasodilator-stimulated phosphoprotein (VASP...

Thyroid Hormones (TH) act on multiple metabolic process influencing the concentration and activity of numerous enzymes, the metabolism of substrates, vitamins and minerals, and the response of target tissues to several hormones. These TH have critical roles in cell differentiation, growth, and regulation of oxygen consumption and thermogenesis [1]. Thyroid disease occurs when the gland is enlar...