نتایج جستجو برای: t regulatory cells

تعداد نتایج: 2027586  

ژورنال: پژوهش در پزشکی 2015

Aim and Background: it seems that population of regulatory T cells increases in many malignancies leading to suppression of effector immune responses and thereby to progression of the disease. We aimed to assess infiltration of the regulatory T cells into tumor environment in women with breast carcinoma. Methods: in a control-case study, 9 malignant tumor tissues from invasive intraductal breas...

شبیری, سعیده سادات, جعفری, نرگس, عابدیان کناری, سعید, محمدنیا افروزی, موسی,

T lymphocytes have been characterized to different subsets such as cytotoxic T, Thelper1 (Th1), Th2, Th3, Th9, Th17, and regulatory T cells. Each of these subsets have specific function which distinct them from other lymphocytes. Regulatory T lymphocytes are effective cells in immune system that play an important role in cancers, autoimmune and infectious diseases. Two main subsets of regulator...

Journal: :iranian journal of medical sciences 0
nidhal abdul-auhaimen department of microbiology, alnahrain college of medicine p.o. box 12444, baghdad, iraq zaman i. l. al-kaabi department of microbiology, alnahrain college of medicine p.o. box 12444, baghdad, iraq

the purpose of this study was to determine the role of streptococcal m protein in naturally-occurring cd4+cd25+ regulatory t cells (ntregs) function and development in rheumatic heart disease in iraqi patients. streptococcus pyogenes was isolated for subsequent m protein extraction. also, peripheral blood ntregs and cd4+ t cells were isolated by using magnetic cell separation system. tissue cul...

ژورنال: پژوهش در پزشکی 2016

Background: Lymph node stromal fibroblasts are interconnected with TCD4+ cells and affect their phenotype and function. Understanding the nature of these interactions under unusual conditions like infections will help to their application in control and regulation of immune responses. Materials and methods: Lymph node fibroblasts were affected in BCG primed immune environment by both in-...

Journal: :avicenna journal of medical biotechnology 0

background: it seems that the success of vaccination for cancer immunotherapy such as dendritic cell (dc) based cancer vaccine is hindered through a powerful network of immune system suppressive elements in which regulatory t cell is the common factor. foxp3 transcription factor is the most specific marker of regulatory t cells. in different studies, targeting an immune response against regulat...

Journal: :iranian journal of immunology 0
samira ghorbani gazar department of immunology alireza andalib department of immunology mohammad hashemi department of internal medicine, isfahan medical school, isfahan university of medical sciences, isfahan, iran abbas rezaei department of immunology

background: atherosclerosis is a multifactorial disorder with chronic inflammatory conditions in which immune cells play a significant role in its pathogenic process. regulatory t cells (treg), as a part of immune system, are involved in controlling autoimmune and inflammatory diseases. quantitative and/or functional alteration of tregs has been shown to play an atheroprotective role and may al...

Journal: :iranian journal of immunology 0
hamideh mesali department of immunology, school of medicine abolghasem ajami department of immunology, school of medicine hadi hussein-nattaj department of immunology, school of medicine alireza rafiei department of immunology, school of medicine zeinab rajabian department of immunology, school of medicine hossein asgarian-omran department of immunology, school of medicine vahid hosseini

background: regulatory t cells (tregs) and myeloid-derived suppressor cells (mdscs) are two main regulatory cells modulating the immune responses in inflammation and cancer. objective: to investigate and compare tregs and mdscs in peptic ulcer and gastric cancer. methods: patients with dyspepsia were selected and divided into three groups of non-ulcer dyspepsia (nud, n=22), peptic ulcer disease...

Journal: :modares journal of medical sciences: pathobiology 2010
tayebeh hashempoor taravat bamdad shahin merat fazel sahraneshin samani kambiz bagheri

objective: hepatitis c virus (hcv) is one of the most relevant persistent infections afflicting the human population. control of viral replication in hcv infection has been associated with the cellular component of the host immune response. several mechanisms have been proposed to explain this abnormal immune response, among them an altered activity of regulatory t cells (tregs) being the most ...

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