lupus erythematosus (le) is an autoimmune disease. the mortality rate and causes of death are different in various countries. the present study is done to find out the causes of mortality in the systemic lupus erythematosus (sle) patients in lupus unit of rheumatology research center and other wards of shariati hospital. this study was retrospective according to medical records of patients who ...

Exudative erythema multiforme is an acute self-limited skin disease often associated with infections (usually viral), and also with systemic diseases and drugs. We report the case of a 39-year-old woman diagnosed with systemic lupus erythematosus, who presented at the emergency clinic with exudative erythema multiforme which started 10 days after taking amoxicillin and clavulanic acid for tonsi...

Erythema multiforme (EM) and systemic lupus erythematosus (SLE) are common diseases. Their coexistence is known as Rowell syndrome (RS), first described in 1963. Only few cases of RS have been described and some of them questioned its existence. We present two cases of SLE in the setting of a newly developed EM-like eruption, which shares many similarities with the so-called Rowell syndrome.

central nervous system ranks among the favorite sites to get involved by nocardia astroides. this opportunistic organism complicates many disorders characterized by cellular or humoral immunity disturbances.a 36-year-old woman is being presented, known to have systemic lupus erythematosus (sle) and having received a two year course of corticosteroid treatment. cerebellar abscess was found on di...

A case of systemic lupus erythematosus is described in which for 10 years the only significant findings were erythema multiforme and vasculitis. Gross hepatosplenomegaly with persistent pancytopenia developed, and bone marrow examination revealed the presence of sideroblasts. The patient's condition deteriorated, and subsequently she developed a severe bleeding tendency, terminating in erythrol...

background: systemic lupus erythematosus (sle) has various presentations in children. hematologic abnormalities is common in childhood onset of sle, however, isolated thrombocytopenia is relatively rare. thus, we present a child with isolated thrombocytopenia as a rare presentation of sle. case presentation: a 12-year-old boy with chief complaints of loss of appetite, weight loss, decreased pla...

a twelve year old girl, an established case of systemic lupus erythematosus, was referred to us suffering from diplopia and nasal speech for a period of 3 months. neurological examination was conducted which revealed a right-sided sixth nerve palsy and a pulsatile nasopharyngeal mass. neurodiagnostic imaging studies confirmed a giant intracavernous internal carotid aneurysm. the malady of the a...

A patient from Southeast Asia was diagnosed with systemic lupus erythematosus. One year later, she experienced exacerbation of skin lesions and was diagnosed with erythema nodosum leprosum. Upon treatment, the patient developed hemophagocytic lymphohistiocytosis with multi-organ failure and died from invasive fungal infection. Hemophagocytic lymphohistiocytosis has to our knowledge, not previou...

at present, some clinical presentations and serological parameters such as products of complement activation and elevation of autoantibodies (e.g. dsdna antibodies), erythrocyte sedimentation rate (esr), levels of c-reactive protein (crp), or cytokines such as il-2/il-2 receptor, il-6 and il-10 are used as indirect serological markers with variable degrees of significance. to date, no specific ...

the central immunological disturbance in systemic lupus erythematosus (sle) is autoantibody production. some of these antibodies affecting components of the cell nucleus are the major characteristics of sle. the present study was aimed to assess importance of anticardiolipin (acl) antibody and its association with clinical state in sle patients. a cross sectional study was performed on 100 pati...