Solutions to problems move only very slowly between different disciplines. Transfer can be greatly speeded up with suitable abstraction and classification of problems. Russian researchers working on the TRIZ (Teoriya Resheniya Izobretatelskikh Zadatch) method for inventive problem solving have identified systematic means of transferring knowledge between different scientific and engineering dis...

—“When you’re movin’ in the positive, your destination is the brightest star.” Stevie Wonder, “Master Blaster (Jammin’),” 1980 This is the last of several commentaries solicited by the Editor on the occasion of the 50th anniversary of our society. Whereas previous installments have reected on key episodes in the past, this one concerns the future. The distant future is hard to predict, except ...

Background: Understanding the differences in genetics of malignancies is crucial for therapeutic decisions. This systematic review was conducted to evaluate the current evidence on genetics of bone tumors in the context of pediatric cancer. Material and Methods: We performed a systematic review of the literature published on genetics of pediatrics bone tumors, using PubMed, Google scholar,...

Martin Plath1,2,3,4) (1 Unit of Animal Ecology, Department of Biochemistry and Biology, University of Potsdam, Maulbeerallee 1, 14469 Potsdam, Germany; 2 Unit of Evolutionary Biology and Systematic Zoology, Department of Biochemistry and Biology, University of Potsdam, Karl-Liebknecht-Str. 24-25, 14476 Potsdam, Germany; 3 Department of Zoology, University of Oklahoma, 730 Van Vleet Oval, Norman...

Systems biology aims at achieving a system-level understanding of living organisms and applying this knowledge to various fields such as synthetic biology, metabolic engineering, and medicine. System-level understanding of living organisms can be derived from insight into: (i) system structure and the mechanism of biological networks such as gene regulation, protein interactions, signaling, and...