For more than half a century free radical-induced alterations at cellular and organ levels have been investigated as a probable underlying mechanism of a number of adverse health conditions. Consequently, significant research efforts have been spent for discovering more effective and potent antioxidants / free radical scavengers for treatment of these adverse conditions. Being by far the most u...

the phenolic compounds of pomegranate (punica granatum l.) peel extracted by two methods (solvent and ultrasound-assisted) with five solvents (acetone, methanol, ethanol, water and ethyl acetate) were compared with supercritical fluid extraction (sfe). the total phenolic compounds were determined according to the folin-ciocalteu reagent using tannic acid as standard. the overall results showed ...

An overview is provided of the cancer chemoprevention actions of phenolic antioxidants and 6-ethoxy-1,2-dihydro-2,2,4-trimethylquinoline (ethoxyquin). These agents principally appear to exert their beneficial effects through induction of phase II drug-metabolizing enzymes such as glutathione S-transferase (GST). The requirement for oxidative metabolism of the synthetic antioxidants to carbonyl-...

The food industry is becoming more specialized and processing methods are continuously being developed to meet consumer needs. Consumers demand products that are safe and preferably free of synthetic additives. These additives are associated with health effects, in most cases without reasonable justification. Consequently, consumers are looking for clearly labelled products that guarantee the a...

      Butyl-hydroxytoluene (BHT) is one of the major synthetic antioxidants with a wide range usage. Replacement of artificial antioxidants with natural antioxidants is highly considered. In this research, the antioxidant activity of Juniperus excelsa was investigated by using reducing power, DPPH radical scavenging and inhibition of lipid peroxidation. Also, the amounts of phenolic an...

the oxidation of lipids change organoleptical properties, nutritional value and shelf life of oils, and produce undesirable compounds that are not safe for customer”s health. there is many methods for prevention of oxidation such synthetic antioxidants, (bha, bht, tbhq, gallatester).synthetic antioxidants, have undesirable effects such cancer, motation in human body, therefore it was removed fr...

Ultrasound-assisted micellar extraction of phenolic antioxidants from spices has been developed for the first time. The effect of the surfactant nature and its concentration on the extraction efficiency has been evaluated. Electrogenerated hexacyanoferrate(III) ions have been used as coulometric titrants owing to their selectivity towards phenolic antioxidants. The best recovery of phenolic ant...

Researchers have reported that the phenolic antioxidants vitamin E and butylated hydroxyltoluene (BHT) effect on cultured cells and human low-density lipoprotein is disrupted by various synthetic chemical compounds and Cu2+ involved in reactive oxygen species (ROS) generation by redox reaction. In this paper, information involved in prooxidative action of vitamin E and BHT in cultured anuran le...