I do not intend to give an account of the changing philosophies concerning the aetiology and treatment of the disease which followed upon Hirschsprung's (1888) first presentation of it as an entity in 1886. It required about 60 years of vague or wrong ideas to find the key to our present knowledge. That happened when our attention was diverted from the characteristic megacolon and was focused o...

I do not intend to give an account of the changing philosophies concerning the aetiology and treatment of the disease which followed upon Hirschsprung's (1888) first presentation of it as an entity in 1886. It required about 60 years of vague or wrong ideas to find the key to our present knowledge. That happened when our attention was diverted from the characteristic megacolon and was focused o...

I do not intend to give an account of the changing philosophies concerning the aetiology and treatment of the disease which followed upon Hirschsprung's (1888) first presentation of it as an entity in 1886. It required about 60 years of vague or wrong ideas to find the key to our present knowledge. That happened when our attention was diverted from the characteristic megacolon and was focused o...

Convergent effects of elevation on functional leaf traits within and among species Quentin D. Read*, Leigh C. Moorhead, Nathan G. Swenson, Joseph K. Bailey and Nathan J. Sanders Department of Ecology and Evolutionary Biology, University of Tennessee, Knoxville, Tennessee, 37996 USA; Rocky Mountain Biological Laboratory, Crested Butte, Colorado, 81224 USA; and Department of Plant Biology, Michig...

Since 1948, a total of 89 patients with an aganglionic megacolon have been treated at the Children's Hospital of the Helsinki University Clinic. There were 68 cases of Hirschsprung's disease, and in 21 cases the anomaly had developed with anal atresia. In nine cases Hirschsprung's disease caused death in early infancy. Operations were performed in 59 cases. Three different types of operation we...

FIONA HE, KEVIN HA, ZUZAN CAYCI, MARIA EVASOVICH SWENSON, M. LUIZA CARAMORI, KHALID AMIN, MICHAEL A. LINDEN, AND CELALETTIN USTUN* Division of Hematology-Oncology and Transplantation, Department of Medicine; Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, Minnesota; epartment of Radiology, University of Minnesota, Minneapolis, Minnesota; Department of Surg...