The energetics underlying the expansion of fusion pores connecting biological or lipid bilayer membranes is elucidated. The energetics necessary to deform membranes as the pore enlarges, in some combination with the action of the fusion proteins, must determine pore growth. The dynamics of pore growth is considered for the case of two homogeneous fusing membranes under different tensions. It is...

The mechanism of water permeation across the sarcolemma was characterized by examining the kinetics and temperature dependence of osmotic swelling and shrinkage of rabbit ventricular myocytes. The magnitude of swelling and the kinetics of swelling and shrinkage were temperature dependent, but the magnitude of shrinkage was very similar at 6 degrees, 22 degrees, and 37 degrees C. Membrane hydrau...

i ntroduction: our study was designed to assess the effect of the submucosal injection of dexamethasone on postoperative discomfort after surgical removal of impacted mandibular third molars. m at erials and methods : twenty six patients with bilaterally bony impacted mandibular third molars were recruited to this split mouth study. on the study side, prior to surgery, 8 mg of dexamethasone was...

results presence of soy pc improved mechanical properties, lowered swelling ratio and increased stability of the films. solubilizing activity of phospholipid resulted in higher flux of drug release from formulation containing higher amount of soy pc. antifungal efficacy of formulations was confirmed against two species of dermatophytes in vitro. conclusions this topical composite film had the p...

We report the formation of wave-like structures and nanostructured fuzzes in the polycrystalline tungsten (W) irradiated with high-flux and low-energy helium (He) ions. From conductive atomic force microscope measurements, we have simultaneously obtained the surface topography and current emission images of the irradiated W materials. Our measurements show that He-enriched and nanostructured st...

We have previously reported the use of hydrogel particles as the draw agent for forward osmosis desalination. In the present work, the effects of draw agent, feed concentration and membrane on the process performance were systematically examined. Our results showed that the incorporation of carbon filler particles in polymer hydrogels led to enhanced swelling ratios of the draw agents and thus ...

results the mean kt/v was 1.27 ± 0.28 in high-flux and 1.10 ± 0.32 in low-flux membrane which, these differences were statistically significant (p = 0.017). the mean of urr was 0.65 ± 0.09 in high-flux and 0.61 ± 0.14 in low-flux membrane, which these differences were not statistically significant (p = 0.221). patients and methods forty hemodialysis patients participated in this cross-over clin...

In electrical discharge machining (EDM), gap control is the key to stable processing; plays a significant role in EDM. To determine influence of on material removal and melt pool movement, which are two fundamental issues EDM, high-speed photography molecular dynamics (MD) simulations were used study process. Research results demonstrate that has during A smaller width produces more larger remo...

The purpose of this study was to investigate the time course of the volume-regulatory response and intracellular sodium concentration ([Na(+)](i)) in the principal cells of rat kidney outer medulla collecting duct (OMCD) epithelia during acute swelling in hypotonic medium. Hypotonic shock was created by PBS diluted with 50% of water. Changes in cell volume were measured with calcein quenching m...