Positron emission tomography (PET) has been widely used in early diagnosis of tumors. Though standardized uptake value (SUV) is a common diagnosis index for PET, it will be affected by the size of the tumor. To explore how the tumor size affects imaging diagnosis index, dynamic PET images were simulated to study the relationship between tumor size and the imaging diagnosis index. It was found t...

The purpose of this study is to assess predictive value of the positron emission tomography (PET) with 18F-fluoro-deoxyglucose (FDG) for recurrence and survival after radiotherapy (RT) for non-small cell lung cancer (NSCLC). One hundred forty-nine patients underwent pretreatment PET (n = 67) or PET/computed tomography (CT) (n = 82) and definitive RT for NSCLC. We evaluated the relationship betw...

UNLABELLED No validated predictive biomarkers for antiangiogenic treatment of metastatic renal cell carcinoma (mRCC) exist. Tumor vascular endothelial growth factor A (VEGF-A) level may be useful. We determined tumor uptake of (89)Zr-bevacizumab, a VEGF-A-binding PET tracer, in mRCC patients before and during antiangiogenic treatment in a pilot study. METHODS Patients underwent (89)Zr-bevaciz...

We have studied the possible relationship between the immunohistochemical expression of p16 and the maximum standardized uptake value (SUV max) of F-18 fluorodeoxyglucose-positron emission tomography (F-18 FDGPET) in 49 patients with non-small cell lung cancer (NSCLC). Immunohistochemical negativity of p16 was verified in 71.4 % of the patients, higher in squamous cell carcinomas than in adenoc...

BACKGROUND Fluorine-18 ((18)F) fluorodeoxyglucose (FDG) positron emission tomography (PET) is limited in its evaluation of brain tumors due to the high basal activity of the cerebral cortex and white matter. Carbon-11 methionine ((11)C MET) has little uptake under normal conditions. We prospectively investigated the uptake of (18)F FDG and (11)C MET PET in patients with craniopharyngioma prior ...

Figure 1 (A) Positron emission tomography CT (PET-CT) scan shows a hypermetabolic lesion located superficial to the lower sternum (arrow), measuring about 3.80×4.77×4.84 cm. SUV max=12.9. (B) PET-CT scan shows a hypermetabolic lesion located in the right first intercostal space with erosion of the first rib (arrow), measuring about 3.25×5.62×4.25 cm. SUV max=10.8. (C) PET-CT scan shows a hyperm...

BACKGROUND Careful clinical staging in patients with malignant pleural mesothelioma (MPM) is fundamental in management planning. Positron emission tomography/computed tomography (PET/CT) is increasingly recognized as an important staging modality. OBJECTIVES The purpose of this study was to assess whether the metabolic activity of the pleural tumor detected with PET/CT correlates with specifi...

Purpose: The purpose of the present study is to evaluate the value of dual-time-point F-18 FDG PET/CT imaging in malignant lymphoma (ML) to differentiate between benign lesions and residual or relapsing malignant lesions. Patients and methods: This prospective study included 252 lymph nodes in 60 patients. F-18 FDG PET/CT scan was performed at 50 min (early scan) and at 100 min (delayed scan) a...

BACKGROUND We previously correlated non-Hodgkin's lymphoma (NHL) histology with (18)fluoro-2-deoxyglucose-positron emission tomography (FDG-PET) intensity: a standardized uptake value (SUV)>10 predicted aggressive lymphoma with >80% certainty and an SUV >13, with >90% certainty. PATIENTS AND METHODS To evaluate SUV in transformed lymphoma, we identified all FDG-PET scans for NHL at Memorial S...

Objective(s): Studies have reported that invasive ductal carcinoma (IDC) with coexisting ductal carcinoma in situ (DCIS) show lower metastatic potential and recurrence and better overall survival than pure IDC. In this study, we assessed F-18 fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) imagesof patients with newly diagnosed IDC to...