a 27 year old patient presented with primary infertility of 3 years' duration and also a history of myomectomy (5 years ago) was referred to our infertility clinic for investigation of infertility. the latest hysterosalpingography (hsg) revealed an obstructed left fallopian tube with apparently a unicornuate uterus with luminal contour irregularity and normal left fallopian tube (figure 1). sig...

Thousands of women experience uterine factor infertility (UFI).1 Some are born without a womb (Müllerian agenesis)2; others have had a hysterectomy for a myriad of uterine-related pathologies. Many of these women, whether suffering from congenital or acquired uterine infertility, retain a strong desire to be able to bear their own biological child.3 Currently, the only clinically tested option ...

The transfer of preimplantation embryos to a surrogate female is a required step for the production of genetically modified mice or to study the effects of epigenetic alterations originated during preimplantation development on subsequent fetal development and adult health. The use of an effective and consistent embryo transfer technique is crucial to enhance the generation of genetically modif...

s:1640:"Background: Surrogacy is one of the most controversial procedures in infertility treatment. Despite increasing of using this technology in Iran, there are few practical data about surrogacy. There isn't any study assessing experiences of commissioning mothers about surrogate mother selection. The purpose of this study was exploring of commissioning mothers' experiences in sele...

OBJECTIVE To evaluate the validity of self-reported hysterectomy against the gold standard of uterine visualisation using pelvic ultrasound. DESIGN Prospective cohort study. SETTING UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS) based in 13 National Health Service (NHS) Trusts in England, Wales and Northern Ireland. PARTICIPANTS Between April 2001 and October 2005, 48 215 po...

Motherhood is no longer a simple concept. Black’s Law Dictionary defines “mother” as “a woman who has given birth to or legally adopted a child.” Recent advances in reproductive technologies have called into question this basic definition of motherhood. Through in vitro fertilization, it is possible to extract an egg from one woman and implant the fertilized egg into the uterus of another woman...

in this paper, we have outlined the surrogate management framework for optimization of expensive functions. an initial simple iterative method which we call the “strawman” method illustrates how surrogates can be incorporated into optimization to stand in for the most expensive function. these ideas are made rigorous by incorporating them into the framework of pattern search methods. the smf al...