Background . The supplementary motor area is a part of the medial frontal cortex, that located just anterior to primary cortex entirely within interhemispheric fissure. This belongs traditionally secondary and perhaps it least studied region brain. While functions symptoms damage premotor areas have been well known described for long time, study has limited fundamental neuroimaging electrophysi...

Different portions of the SMA appear to be engaged by different types of neurological functions. It is important to identify the functional activation of SMA in terms of planning the surgical strategy. Our unpublished data from M.D. Anderson suggest that resection of the site of SMA activation based on fMRI is an important parameter for predicting the postoperative neurological deficit. Also, p...

Rationale: Surgical removal of the lesions involving the supplementary motor area, results in immediate motor and speech deficits, which in most cases are reversible. Aim: Extent of removal of the supplementary motor area influences the post-operative deficits. Patients and Methods: 12 cases are included in this study, representing lesions involving the supplementary motor area by intra-axial g...

Neuronal underpinnings of auditory verbal hallucination remain poorly understood. One suggested mechanism is brain activation that is similar to verbal imagery but occurs without the proper activation of the neuronal systems that are required to tag the origins of verbal imagery in one's mind. Such neuronal systems involve the supplementary motor area. The supplementary motor area has been asso...

We used high-frequency repetitive transcranial magnetic stimulation (rTMS) to study the role of the mesial frontocentral cortex (including the supplementary motor area) in the organization of sequential finger movements of different complexity in humans. In 15 subjects, rTMS was randomly applied to the scalp overlying the region of the supplementary motor area and over other positions, includin...

BACKGROUND AND PURPOSE The purpose of this study was to assess supplementary motor area (SMA) activation during motor, sensory, word generation, listening comprehension, and working memory tasks by using functional MR imaging (fMRI). Human supplementary motor area (SMA) has been shown to play roles in motor control and other various functions such as sensory, speech expression, and memory. Howe...

The supplementary motor area (SMA) is a key structure involved in behavioral planning and execution. Although many reports have indicated that SMA is organized somatotopically, its exact organization remains still unclear. This study aimed to functionally map SMA using functional magnetic resonance imaging (fMRI) and validate the fMRI-SMA by electrocortical stimulation (ECS) and postsurgical sy...