Incontinentia Pigmenti, also known as Bloch-Sulzberger syndrome, is a rare X-linked dominant disorder considered to be lethal in males. The syndrome usually presents at birth or shortly thereafter and the skin rash evolves in the classic four stages of vesicular, verrucous, hyperpigmented, and hypopigmented lesions following a blaschko linear distribution. Here we present an unusual case of Inc...

The course and histologic skin signs are described at the stage of inflammation in 2 cases of incontinentia pigmenti (IP) or the Bloch-Sulzberger syndrome. In the authors' opinion, the pigmentary stage of skin lesion in IP does not replace the warty stage, but accompanies it or the inflammatory one as blebs disappear. In IP, the latter contain eosinophils; there is plasma and cell infiltration ...

Incontinentia pigmenti (IP; Bloch-Sulzberger syndrome) is a rare, genetic syndrome inherited as an X-linked dominant trait. It primarily affects female infants and is lethal in the majority of males during fetal life. The clinical findings include skin lesions, developmental defects, and defects of the eyes, teeth, skeletal system, and central nervous system. Cardiovascular complications of thi...

Occluded sweat ducts are the hallmark of miliaria. The occlusions were thought to be due to biofilm or “slime” producing Staphylococcus epidermidis. Sulzberger first saw occluded ducts in eczema and 60 years later, these were rediscovered and shown to be due to many different species of staphylococci, including S. aureus, epidermidis, tenuis and many others. These occlusions also trigger the ac...

Scientific Events: The Birthrate of Great Britain; The Botanic Garden of the University of Cambridge; Recommendations for the Care of the Medically Indigent; New and Bare Instruments; The Virginia Academy of Science Research Endowment .................. ... ... 51 Special Articles: Demonstrating the Presence of Sulfonamides in the Tissues: COMMt. MARION B. SULZBERGER, M.0., U.S.N.R. and OTHERS....

During the past two decades anaphylactic phenomena induced by simple chemical compounds have been studied experimentally by a few investigators, especially by Landsteiner and Sulzberger and their collaborators in the United States of America. We also have carried out several experiments along this line, and our observations conducted in this laboratory are briefly described herein without refer...