BACKGROUND Epidural administration of neostigmine appears to be safe in the obstetric population. Recently, few studies have concluded 10 μg sufentanil to be an effective adjuvant with epidural neostigmine in providing labor analgesia. However, no study has evaluated the analgesic effect of epidural butorphanol with neostigmine for the same. MATERIALS AND METHODS The parturients were randomly...

A 60-year-old man, without dental articulation disorders or a history of dislocation of the temporomandibular joint, was admitted to our intensive care unit after surgery for aortic dissection. He had been intubated without complication 4 days earlier. On the day of surgery, he was sedated with midazolam and sufentanyl, and received a neuromuscular blocker. Using a flexible endoscope, upper gas...

Using Xenopus laevis oocytes coexpressing mammalian m-opioid receptors (MORs), b-adrenergic receptor kinase 2 (b-ARK2) [also called G protein-coupled receptor kinase (GRK3)], and b-arrestin 2 (b-arr 2), we compared the rates of b-ARK2 (GRK3)and b-arr 2-mediated homologous receptor desensitization produced by treatment with opioid agonists of different efficacies. The response to MOR activation ...