Behavioral genetic studies have provided insights into why early substance use initiation is associated with increased risk for disorder. Few genetically informative studies, however, have operationalized initiation as the timing of first use and simultaneously modeled the timing of initiation and problematic use of multiple substances. Such research can help capture the risk associated with ea...

Abstract Background Pregabalin abuse is increasing worldwide and frequently comorbid with another psychiatric disorders including generalized anxiety, major depression, personality disorders, suicide. Eighty-three patients meeting DSM-IV criteria for substance related to pregabalin were identified from the addiction clinic of El Khanka Psychiatric Hospital in Egypt this observational cross-sect...

Life traumatic experiences are major health problems in different communities. Early trauma exposures such as physical and sexual abuse, and midlife traumatic events like exposing to disasters are predisposing and precipitating risk factors for many psychiatric disorders, although many people facing to trauma may not show any problematic symptoms and are quite resilient. Neuropsychiatric eviden...

INTRODUCTION Evidence suggests that comorbid psychopathology can negatively affect treatment outcomes in substance users. In South Africa, limited information exists regarding the prevalence, nature and role of psychiatric comorbidity in substance users. This study examined psychiatric comorbidity and its association with specific substance use, and young adult substance users in treatment for ...

Synthetic stimulants can cause hallucinations, aggressive behaviors, death and are sometimes legal. These substances are sold as plant food and bath salts that are "Not for Human Consumption", therefore skirting the 1986 Federal Analogue Act and giving a false pretense of safety. Studies have proved that these substances are toxic, have a high abuse potential, and are becoming extremely prevale...

Few studies have examined the relationship between posttraumatic stress disorder (PTSD), substance use disorder, and dissociation. We studied 77 women with current PTSD and substance dependence, classified into high- versus low-dissociation groups per the Dissociative Experiences Scale. They were compared on trauma- and substance-related symptoms, cognitions, coping skills, social adjustment, t...

Synthetic stimulants can cause hallucinations, aggressive behaviors, death and are sometimes legal. These substances are sold as plant food and bath salts that are “Not for Human Consumption”, therefore skirting the 1986 Federal Analogue Act and giving a false pretense of safety. Studies have proved that these substances are toxic, have a high abuse potential, and are becoming extremely prevale...

background:  the  current study examined race and ethnic differences in the separate and combined (additive) effects of anxiety, depression and problem drinking on the baseline and trajectory of subjective health among adult men in the united states. methods:  this longitudinal study used data from the fragile families and child well-being study. we included 4655 men, composed of 2407 blacks, 1...

OBJECTIVE To identify the association between panic disorder and licit and illicit substance use in the population provided with primary care in the southern Brazil. METHODS This is a cross-sectional study with patients from three primary care centers. We used the Alcohol, Smoking and Substance Involvement Screening Test (ASSIST) to evaluate substance use and the Mini International Neuropsych...