We analyzed 56 O2 equilibrium curves of fresh human blood, each from 0 to 150 Torr Po2. The data were collected over ranges of values for the 2,3-diphosphoglyceric acid-to-hemoglobin concentration ratio [DPG]/[Hb] of 0.2-2.7, for pH of 7.0-7.8, and for Pco2 of 7-70 Torr. Each curve was characterized according to the Adair scheme for the stepwise oxygenation of Hb, and the resulting constants (a...

On the assumption that antibody is added to virus particles in a stepwise manner and that the reaction follows the law of mass action, a theoretical equation for the equilibrium state of virus neutralization reactions has been deduced. The theory has been found to be in reasonable accord with the available data for the neutralization of bacterial viruses and can be applied also to data for the ...

The aim is to investigate the eff ects of stepwise blanching and its combination with drying on rheological properties and change of color in pumpkins (Cucurbita moschata). 1 cm thick samples were immersed in water at 55 °C for diff erent times, followed by diff erent holding times prior to inactivation of the enzyme (97 °C/5minutes). Controled samples were obtained after blanching at 97 °C for...

Liraglutide is a human glucagon-like peptide-1 (GLP-1) analogue approved for the treatment of type 2 diabetes. It is based on human GLP-1 with the addition of a 16-carbon fatty acid, which facilitates binding to plasma proteins, thus prolonging the elimination half-life and allowing once-daily administration. It has not been possible to quantify liraglutide protein binding by ultrafiltration (t...

The fractionation of the oxygen isotopes in the water collected by stepwise dehydration of CUS04 -5H20 has been measured for the crystallization temperatures 25, 40 and 50 °C. From X-ray and neutron diffraction studies it is known that three different kinds of water, differing in their binding in the crystal, exist in CuS04 ,5 H20. On the basis of the results reported here it is concluded that ...

Ettringite-based thermochemical energy storage has been recommended to be used in buildings for thermal supply because of its low material cost (<1000 €/m3), working temperature and high capacity. However, several physicochemical properties ettringite were still not clear, such as reversible reaction enthalpies, thermodynamic equilibrium, kinetics the dehydration/hydration reactions. In this st...

The binding of hexanoic, octanoic, and decanoic acids to defatted human plasma albumin was measured by equilibrium dialysis at 37” in a calcium-free Krebs-Ringer phosphate buffer, pH 7.4. The results were analyzed in terms of multiple stepwise equilibria. For each of the albumin binding sites, the magnitude of the equilibrium constants increased as the chain length of the acid increased: decano...

The high-affinity radioligand [(18)F]fallypride (FP) is frequently used for quantification of striatal/extrastriatal D(2/3) receptors and the receptor occupancies of antipsychotics (APs). Its 110 minutes half-life allows long scan durations. However, the optimum scan duration is a matter of debate. This investigation focuses on scan-duration-related effects on simplified reference tissue model ...