The word, super-refectory is coined recently in status epilepticus (SE) when the seizures continue unabated for a day or more, despite rigorous management , leading to subsequent neuronal injury, most of the times and even death [1]. The SuperRefractory Status Epilepeticus is a rare but not uncommon type of ongoing seizure activity and the exact pathophysiology is still not yet studied well. Th...

Investigators from Baylor College of Medicine studied the efficacy of lacosamide in pediatric status epilepticus (SE).

BACKGROUND Convulsing Status Epilepticus (CSE) is a common paediatric emergency especially under 24 months age group. Present study was done to know causes of Status Epilepticus (SE) and outcome during admission and at the time of discharge. METHODS A descriptive study in children 2 months to 15 years of age, admitted in Department of Paediatrics, Ayub Medical College, Abbottabad with first s...

PURPOSE Status epilepticus (SE) is a neurological emergency, characterized by high short-term morbidity and mortality. We evaluated and compared two scores that have been developed to evaluate status epilepticus prognosis: STESS (Status Epilepticus Severity Score) and EMSE (Epidemiology based Mortality score in Status Epilepticus). METHODS A prospective observational study was performed on co...

Target disease: Status Epilepticus (SE). Status epilepticus is a true neurologic emergency associated with significant morbidity and mortality. It has been estimated that there are between 120,000 and 200,000 cases of status epilepticus in this country each year resulting in as many as 55,000 deaths. 1 An incidence of between 6.2 and 18.3 per 100,000 persons has been reported in the United Stat...

Background Super refractory status epilepticus (SRSE) is an important and recently recognized neurological emergency. Purpose In view of paucity of studies on SRSE, we report the frequency, etiology and outcome of SRSE. Methods In a hospital-based observational study during 2013 to 2016, consecutive patients with SRSE [persistence of status epilepticus (SE) for 24 h or more, or recurrence o...

Head and eye turning is frequently observed during seizures. Versions with tonic and/or clonic symptoms can be differentiated from smooth head deviations. Head turning as a prominent symptom of status epilepticus has not previously been reported. We present eight case reports, (7 women/1 man, mean age 41 years, median 41.5, range 10 to 74), of status epilepticus (SE), with head turning as a pro...

Status epilepticus is a life threatening condition with a high mortality rate in spite of aggressive treatment. There is little consensus on third and fourth line approaches in refractory cases. While electroconvulsive therapy (ECT) has been employed successfully as a treatment for refractory epilepsy and status epilepticus (SE) after exhausting conventional therapy, its use for pediatric patie...

OBJECTIVES To elucidate factors that contribute to the development of status epilepticus (SE) and determine prognostic factors and the impact on 30-day survival. DESIGN Retrospective review of medical records. SETTING University of Virginia Health System. Patients Thirty-five patients with SE secondary to a tumor, either primary or systemic, or its treatment. MAIN OUTCOME MEASURES Seizure...

What is the long-term mortality after a first episode of afebrile status epilepticus (SE)? Do seizure type, cause, and duration of SE affect long-term mortality? Inception cohort followed until death or 10 years after initial SE. P a t i e n t s 145 patients (50% women) who had a first episode of afebrile SE (a seizure lasting ≥ 30 min or repeated seizures over a period ≥ 30 min without recover...