The purpose of this research work was to develop a novel, sensitive and accurate analytical method for quantification of 12 residual solvents in Dapagliflozin Amorphous by using a static headspace gas chromatography (HSGC) coupled with flame ionization detector (FID). Methanol, Ethanol, Diethyl ether, Methyl acetate, Dichloromethane, Ethyl acetate, Tetrahydrofuran, Cyclohexane, Isopropyl acetat...

This study demonstrates the use of solid-phase microextraction (SPME) to extract and pre-concentrate volatile signatures from static air above plastic explosive samples followed by detection using ion mobility spectrometry (IMS) optimized to detect the volatile, non-energetic components rather than the energetic materials. Currently, sample collection for detection by commercial IMS analyzers i...

Volatiles from crushed and intact guava leaves (Psidium guajava L.) were collected using static headspace SPME and determined using GC-PFPD, pulsed flame photometric detection, and GC-MS. Leaf volatiles from four common citrus culitvars were examined similarly to determine the potential component(s) responsible for guava's protective effect against the Asian citrus psyllid (Diaphorina citri Kuw...

An ultra-sensitive gas phase biosensor/tracer/bio-sniffer is an emerging technology platform designed to provide real-time information on air-borne analytes, or those in liquids, through classical headspace analysis. The desired bio-sniffer measures gaseous 17α- ethinylestradiol (ETED) as frequency changes on a quartz crystal microbalance (QCM), which is a result of the interactions of liquid s...

Charcoal tubes are widely used for collecting organic vapor in the atmosphere, and the measurement is usually completed by analyzing an aliquot of the solvent phase following solvent extraction, typically with carbon disuhide. However, the sensitivity of this method is limited and sometimes too low for monitoring contaminants at trace levels in the environmental atmosphere. In this study, the p...