The use of endovascular catheters is a routine practice in secondary and tertiary care level hospitals. Short peripheral catheters have been found to be associated with the risk of nosocomial bacteremia resulting in morbidity and mortality. Staphyloccus aureus is mostly associated with peripheral catheter insertion. This Consensus Document has been elaborated by a panel of experts of the Spanis...

The composition and antimicrobial activity of the essential oils which were obtained from agarwood originated from Aquilaria sinensis (Lour.) Gilg stimulated by the chemical method (S1) were characterized, taking wild agarwood (S2) and healthy trees (S3) respectively as the positive and negative controls. The chemical composition of S1 was investigated by gas chromatography-mass spectrometry (G...

Peptide antibiotics containing lanthionine and 3-methyllanthionine bridges, named lantibiotics are of increasing interest. A new lantibiotic, gallidermin, has been isolated from Staphyloccus gallinarum. Here we report the isolation of its structural gene which we name gdmA. In all lantibiotics so far studied genetically, three peptides can be formally distinguished: (i) the primary translation ...

The ability of peripheral blood monocytes from patients with ulcerative colitis and Crohn's disease to phagocytose and kill a standard strain of Staphyloccus aureus has been studied. Using lysostaphin, a rapidly acting muralytic enzyme, phagocytosis could be accurately differentiated from intracellular killing. When compared with normal healthy individuals and patients with gastrointestinal dis...

Development of synthetic strategies to combat Staphylococcal infections, especially those caused by methicillin resistant Staphyloccus aureus (MRSA), needs immediate attention. In this manuscript we report the ability of aryl-alkyl-lysines, simple membrane active small molecules, to treat infections caused by planktonic cells, persister cells and biofilms of MRSA. A representative compound, NCK...

Antimicrobial activity of methanolic, chloroform, hexane and aqueous stem extracts of Erythrina variegata L. were analyzed against nine bacterial pathogens such as Salmonella typhi, Pseudomonas putida, Pseudomonas aeruginosa, Escherichia coli, Klebsiella sp., Proteus sp., Serratia marcescens, Bacillus circulans, Staphyloccus aureus and five fungal pathogens viz. Aspergillus niger, Aspergillus f...

Xanthan gum (XG) is natural polysaccharides used in food industries as stabilizers and thickener agents. The problem is that some food products are found to be contaminated by pathogenic bacteria such as Escherichia coli (E. coli) and Staphyloccus aureus (S. aureus) that reduce their shelf life. This research aims to synthesize biodegradable antibacterial XG-grafted-poly(N-vinyl imidazole) PVI ...

Pendahuluan: Jamur endofit yang berasal dari biota laut spons diketahui sebagai sumber penghasil berbagai jenis metabolit sekunder. Metabolit sekunder dihasilkan telah dilaporkan memiliki beberapa bioaktivitas termasuk antibakteri. Tujuan: Penelitian ini bertujuan untuk mengetahui aktivitas antibakteri ekstrak etil asetat dan fraksi jamur Penicillium oxalicum diisolasi Homaxinella tanitai terha...

The problem of infection has been persistent in the surgical world even after the introduction of antibiotics. Pathogens that infect surgical wounds can be part of normal flora or acquired from the hospital environment or other infected patients. Staphylococcus aureus, being the normal microbial flora of the skin is one of the commonest causes of wound infection. A total of 1088 pus samples fro...