objective: to investigate the effect of fluoxetine as an ssri on menstrual disorders. materials and methods: in this cross-sectional study 200 women referring to the islamic azad university affiliated hospitals during march 2011- march 2010 were divided into 4 groups. all included patients in this study had the chief complaint of mood disorders in peri- menstrual period. all patients received d...

Background Selective serotonin reuptake inhibitors (SSRIs) have been implicated in contributing to recovery after acute ischaemic stroke. In particular, poststroke initiation of an SSRI has been demonstrated to improve motor recovery. The role of prestroke SSRI use on functional outcomes and stroke recovery is less clear. We aimed to examine the effect of prestroke SSRI use on metrics of hospit...

This prospective cohort study compares the breastfeeding outcomes of women exposed to selective serotonin reuptake inhibitor (SSRI) antidepressants at the time of delivery, those who discontinued use prior to delivery, and those not exposed. Participants include 466 pregnant women who enrolled in the California Teratogen Information Service Clinical Research Program (CTIS) over 10 years. In biv...

BACKGROUND Patients prescribed antiplatelet treatment to prevent recurrent acute myocardial infarction are often also given a selective serotonin reuptake inhibitor (SSRI) to treat coexisting depression. Use of either treatment may increase the risk of bleeding. We assessed the risk of bleeding among patients taking both medications following acute myocardial infarction. METHODS We conducted ...

OBJECTIVE Despite a rapidly growing literature on the efficacy of the selective serotonin reuptake inhibitors (SSRI) in the treatment of juvenile psychiatric disorders, relatively little is described about emotional, behavioral, and cognitive adverse effects associated with their use. To this end we completed a retrospective analysis of medical charts to determine the incidence, nature, and cli...

Background This study aimed to investigate the association between the use of selective serotonin reuptake inhibitors (SSRIs) and the risk of hepatocellular carcinoma (HCC) in patients with chronic hepatitis B virus (HBV) infection. Methods We conducted a population-based cohort study by using claims data from the Taiwan National Health Insurance Research Database (NHIRD). The study cohort co...

BACKGROUND To analyze the necessity of bone densitometry for patients long-term taking selective serotonin reuptake inhibitors (SSRI) over a long period of time, which is one of the risk factors of osteoporosis. METHODS We selected patients from 5 veterans hospitals who took SSRI for more than 2 months while taking bone densitometry on a regular basis. RESULTS Of the 85 patients from a tota...

BACKGROUND Previous research has suggested a link between antidepressants use and the development of cerebrovascular events, but there has never been any study investigating the risk of stroke in obsessive-compulsive disorder (OCD) patients treated with a selective serotonin reuptake inhibitor (SSRI). METHODS A retrospective observational cohort study was conducted using data from the Nationa...

BACKGROUND AND PURPOSE Selective serotonin reuptake inhibitors (SSRIs) have been associated with an increased risk of bleeding but also a possible neuroprotective effect in stroke. We aimed to examine the implications of prestroke SSRI use in hemorrhagic and ischemic stroke. METHODS We conducted a registry-based propensity score-matched follow-up study among first-ever patients with hemorrhag...