(87)Sr/(86)Sr reference maps (isoscapes) are a key tool for investigating past human and animal migrations. However, there is little understanding of which biosphere samples are best proxies for local bioavailable Sr when dealing with movements of past populations. In this study, biological and geological samples (ground vegetation, tree leaves, rock leachates, water, soil extracts, as well as ...

Clastic sediments in the Bengal Fan contain a Neogene history of erosion and weathering of the Himalaya. We present data on clay mineralogy, major element, stable and radiogenic isotope abundances from Lower Miocene-Pleistocene sediments from ODP Leg 116. Nd and Sr isotope data show that the Himalayan provenance for the eroded material has varied little since > 17 Ma. However, from 7 to 1 Ma sm...

The absence of the scavenger receptor A (SR-A)-I/II has produced variable effects on atherosclerosis in different murine models. Therefore, we examined whether SR-AI/II deficiency affected atherogenesis in C57BL/6 mice, an inbred strain known to be susceptible to diet-induced atherosclerotic lesion formation, and whether the deletion of macrophage SR-AI/II expression would modulate lesion growt...

the objective of research was to explore the suitability of lipids like compritol 888 ato and stearic acid as release retardant to develop sustained release (sr) tablets. the sr micromatrices of lipid (s) and glipizide were prepared (lm1- lm6) as intermediate product by fusion method and assessed for various pharmacotechnical properties. micromatrices were formulated as sr tablets (f1-f6) by di...

Atrial fibrillation (AF) is associated with worse outcomes in many cardiovascular diseases. There are few data examining pacemaker implantation rates and indications in patients with AF who undergo transcatheter aortic valve replacement (TAVR). To examine the impact of AF on the incidence of and indications for pacemakers in patients undergoing TAVR, we evaluated data of 1723 patients without p...

Of the many ongoing controversies regarding the workings of the sarcoplasmic reticulum (SR) in cardiac myocytes, two unresolved and interconnected topics are 1), mechanisms of calcium (Ca(2+)) wave propagation, and 2), speed of Ca(2+) diffusion within the SR. Ca(2+) waves are initiated when a spontaneous local SR Ca(2+) release event triggers additional release from neighboring clusters of SR r...

We report Sr isotope anomalies in two Ca·Al-rich inclusions (EKl-4-1 and Cl) of the Allende meteoritewhichalsocontainanomaliesin 0, Mg, Ca, Ba, Nd and Sm. The Sr effects correspond to 84 Sr or 88 Sr deficits of 3.2"too and 0.8%o or to 86 Sr excesses of 1.6%o and 0.4"too. Although it cannot be ascertained in which isotope the anomalies reside, arguments based on the 8 7 Sr abundance indicate tha...

Mountaintop mining (MTM) is the primary procedure for surface coal exploration within the central Appalachian region of the eastern United States, and it is known to contaminate streams in local watersheds. In this study, we measured the chemical and isotopic compositions of water samples from MTM-impacted tributaries and streams in the Mud River watershed in West Virginia. We systematically do...