Systematic observation of 1141 nude mice (Swiss background [corrected] strain) that received human tumor transplants revealed 24 spontaneous tumors, 18 of lymphoreticular origin and 6 pulmonary adenomas. Spontaneous tumors were seen at an average age of 9.1 months, and 22 of the tumors were seen only in that fraction of our group (324 mice) surviving for 5 months or more (22 of 324 X 100 = 6.8%...

Eric F. Martin1, Michael Huang2, Beatrice Madrazo3 and Cynthia Levy1* 1Division of Hepatology, University of Miami Miller School of Medicine, Miami, Florida, USA 2Division of Gastroenterology, University of Miami Miller School of Medicine, Miami, Florida, USA 3Division of Radiology, University of Miami Miller School of Medicine, Miami, Florida, USA Journal of Gastroenterology, Pancreatology & L...

The substrate specificity of hexokinase preparations from Ehrlich ascites cells, a spontaneous adenocarcinoma, Jensen sarcoma, and Walker carcinoma was studied with a number of sugars which differed in structure from glucose at one or more carbon atoms used as substrates. A marked variat ion in specificity was found. The preparations from Jensen sarcoma and Ehrlich ascites cells were relatively...

Expectoration of tumor tissue is a rare presentation in patients with cancer. Thirty cases of various types of tumor, including primary or metastatic lung cancer, have been reported. Endobronchial metastases from various organs are most common, although 9 primary lung cancer cases have been described, including 4 squamous cell carcinomas, 2 bronchogenic carcinoids, one small cell lung carcinoma...

background: one million people are diagnosed with gastric cancer (gc) annually and the prognosis for patients with advanced gc or gastroesophageal junction (gej) cancer is usually poor with a median survival time of 8 to 10 months. recent reports have identified that anti her2 target therapy improved the median survival rate in patients with her2 positive gc; but a wide range of her2 overexpres...