STUDY OBJECTIVE The aim was to evaluate the appropriateness of postal questionnaires in studies of spontaneous abortion in a general population. DESIGN Survey of spontaneous abortions by comparing diagnoses reported in questionnaires to information collected from hospital records and a discharge register. SETTING The study took place in the general community. PARTICIPANTS The study involv...

In a series of 2922 karyotyped spontaneous abortions, 62 were found to be trisomic for chromosome 13, 46 having a simple trisomy and 16 a translocation trisomy. The epidemiology of this series of trisomy 13 conceptuses is presented and compared to that of trisomy 13 ascertained from other populations. In most compared parameters the trisomy 13 spontaneous abortions are very similar. However, th...

Spontaneous abortions in hospitals were analysed from two sources-membership files of the Union of Rubber and Leather Workers (about 10000 women) and records of the personnel of a rubber factory (about 1600 women). Two frequencies of spontaneous abortions were calculated for each population analysed: rate (No spontaneous abortions x 100/No pregnancies) and ratio (No spontaneous abortions x 100/...

Objective: Approximately 15-20% of clinically recognizable pregnancies end in spontaneous abortion. The incidence of chromosomal abnormalities in those abortions is as high as 50%.A modest but clinically important proportion of spontaneous abortions is caused by a balanced chromosomal aberration in one o...

Background: The role of apolipoprotien E polymorphisms do not diagnostic correctly in recurrent pregnancy loss etiology but Apo E has been shown to play an important role in lipid metabolism in pregnancy. We evaluated these polymorphisms in Iranian women with unexplained recurrent pregnancy loss. Materials and Methods: 5 ml Blood were sampling from 81 women with a history of two or more consecu...

OBJECTIVE Adenosine deaminase acts on adenosine and deoxyadenosine metabolism and modulates the immune response. The adenosine deaminase G22A polymorphism (20q.11.33) influences the level of adenosine deaminase enzyme expression, which seems to play a key role in maintaining pregnancy. The adenosine deaminase 2 phenotype has been associated with a protective effect against recurrent spontaneous...

The role of induced (and spontaneous) abortions in the aetiology of secondary sterility was investigated. Obstetric and gynaecologic histories were obtained from 100 women with secondary infertility admitted to the First Department of Obstetrics and Gynaecology of the University of Athens Medical School and to the Division of Fertility and Sterility of that Department. For every patient, an att...

Since the advent of C-banding as a routine diagnostic procedure, the significance of heterochromatic polymorphism has been questioned. Some workers have considered variations in heterochromatin in chromosomes 1 and 9 to be associated with fetal wastage, recurrent abortions, and abnormal phenotypes. Over a 15-month period, this laboratory made a study of the diagnostic significance of heterochro...