background: recurrent spontaneous abortion impacts almost 1% of couples. the sera from women with unexplained recurrent spontaneous abortion (ursa) have toxic effects on embryos that grow in the uterus. therefore, the abnormal condition of the uterus may also affect sperm qualities. objective: the objectives of this study were to search if these sera could induce dna denaturation in sperm nucle...

the measurment of various cytokines may provide a different tool for evaluation of the immune system. recent investigations have shown that the number and function of peripheral natural killer cells (nk- cells) increase during early pregnancy in women with a history of unexplained recurrent spontaneous abortions (rsa). nk-cells activity may be responsible for some cases of rsa. the objective of...

objective herpes simplex virus (hsv) infection during pregnancy may lead to fetal loss. the aim of this study was to explore the infection rate of hsv type 1 and 2 infection associated with spontaneous abortion in a pilot case-control study in two cities of iran in 2010. patients and methods placenta and curettage samples from 35 healthy full term neonates and 35 cases of spontaneous abortion w...

introduction: a factor known to cause thrombophilia in women with recurrent pregnancy loss (rpl) is the a1298c polymorphism of methylenetetrahydrofolate reductase gene (mthfr). this study aimed to determine the association between rpl and this polymorphism in iranian patients. methods: in this case-control study, 30 patients with a previous history of two or more consecutive unexplained abortio...

background & aim: occupational exposures can cause problems such as reproductive system disorders; however, the effects of some exposures, such as psychological stress, have not been investigated yet. this study aims to investigate the effects of women’s psychological stress on obstetric disorders. methods:this historical cohort study was conducted on 1400 working women in mashhad, iran. data c...

ureaplasma urealyticum can colonize women genital tract and be isolated from the amniotic fluid of women with adverse pregnancy outcomes. the association of u. urealyticum with spontaneous abortion remains controversial. the aim of this study was to evaluate the frequency of u. urealyticum infection among pregnant women and its association with spontaneous abortion.in this case-control study we...

Background: Epidemiological evidence suggests that fine particulate air pollution, particularly particles less than 10 microns in diameter (PM10) exposure adversely affects pregnancy outcomes and usually aromatic hydrocarbons such as benzene bound to fine particles. We evaluated the impacts of PM10 and benzene on spontaneous abortion of first trimester of pregnancy in Tehran. Materials and Meth...

background: the termination of pregnancy before 20 th week of gestation is abortion. there is two type of abortion: spontaneous and induce (legal or illegal). the annual number of pregnancy in the world is estimated over 200 million and one third of them is unwanted pregnancy. 95% of unwanted pregnancy is happened in developing country such as iran. in iran, the high prevalence of unwanted preg...