We introduce digital microfluidic interface between solid-phase microextraction (SPME) and liquid chromatography. In the new system, a SPME fiber is used to extract analytes from a complex sample, and is then inserted into a DMF device. Solvent droplets are then used to extract analytes from the fiber with continuous actuation, followed by analysis with liquid chromatography (LC) and mass spect...

Until recently, sample preparation was carried out using traditional techniques, such as liquid-liquid extraction (LLE), that use large volumes of organic solvents. Solid-phase extraction (SPE) uses much less solvent than LLE, although the volume can still be significant. These preparation methods are expensive, time-consuming and environmentally unfriendly. Recently, a great effort has been ma...

After more than 25 years, solid-phase microextraction (SPME) has gained widespread acceptance as a well-automatable and flexible microextraction technique, while its instrumental basis remained mostly unchanged. The novel PAL (Prep And Load solution) SPME Arrow combines the advantages of SPME with the benefits of extraction techniques providing larger sorption phase volumes such as stir bar sor...

In the course of our continuing work on transformation of monoterpenes by microorganisms, the biotransformation of (+)- and (-)-carvone was carried out. The metabolites formed during microbial transformations were screened using a simple, rapid and efficient technique: Headspace-solid phase microextraction (SPME)/GC-MS. The results as well as the application of this technique are described.

Recent improvements in the detection of alkylated aromatic compounds from gasoline accelerants in arson debris use expensive GC-MS-MS instrumentation that is not available to most crime laboratories. This research project uses solid-phase microextraction (SPME), an inexpensive pre-concentration method, to achieve high sensitivities in the analysis of alkylated aromatic compounds.

Lappeenranta University of Technology Faculty of Technology Degree Program in Environmental Technology Ville Luukkonen Determination of chlorophenols from water by solid phase microextraction – ion mobility spectrometry (SPME-IMS) Master’s thesis 2012 86 pages, 38 figures and 5 tables Examiners: Professor, D.Sc. (Tech.) Mika Sillanpää Lic.Sc. (Tech.) Simo Hammo Supervisor: M.Sc. Sanna Holopainen

AbstractThe oldest method for the managing of the illness is the use of medicinal plants. The use of herbal products as the first choice in self-treatment of minor conditions continues to expand rapidly across Iran. This makes the safety of herbal products an important public health issue.Pesticides are used widely in agriculture to increase the production by controlling the harmful insects and...

ABSTRACT Despite the growing popularity of solid-phase microextraction (SPME) among the community of analytical chemists, applications of SPME in the measurement of very hydrophobic organic compounds (VHOCs) have remained limited. This is due, in part, to the difficulty of calibrating SPME devices for VHOCs. Here, we present an analytical procedure used to determine the distribution coefficient...

2 Headspace sampling for gas chromatographic (GC) analysis has many advantages, the most important of which is the elimination of many interferences from the sample matrix. In addition to the standard methods for headspace sampling, the technique of solid-phase microextraction (SPME) has found wide acceptance because it is simple and inexpensive. More recently, single-drop microextraction (SDME...