Spina Gleditsiae is an important herb with various medicinal properties in traditional and folk medicinal systems of East Asian countries. In China through the centuries, it has been traditionally used as a source of drugs for anticancer, detoxication, detumescence, apocenosis, and antiparasites effects. Recently, an increasing number of studies have been reported regarding its chemical constit...

INTRODUCTION Neural tube defects such as anencephaly, spina bifida, and encephalocele are congenital anomalies of the central nervous system. Data on the prevalence of neural tube defects in Kenya are limited. This study characterizes and estimates the prevalence of spina bifida and encephalocele reported in a referral hospital in Kenya from 2005-2010. METHODS Cases were defined as a diagnosi...

Based on a social-ecological theoretical framework, this study sought to identify key individual (attitude toward spina bifida), family (satisfaction with family functioning), and peer (peer support) factors associated with the quality of sibling relationships in families of youths with spina bifida. A cross-sectional sample of 224 siblings of youths with spina bifida, ages 11-18 years, and par...

The systematics of a little known species of north Andean satyrine butterfly, Pedaliodes spina WEYMER, 1912, is overviewed. Geographic range of the species is delimited. The nominate subspecies is identified and a new, widely distributed Ecuadorian subspecies, P. spina bifurcata n. ssp. is described. The ecology of P. spina is briefly discussed. Pedaliodes morenoi pilaloensis PYRCZ et VILORIA, ...

The spatial knowledge of 18 children with spina bifida and 18 healthy control children (matched according to sex, age, and verbal IQ) was investigated in a computer-simulated environment. All children had to learn a route through a virtual floor system containing 18 landmarks. Controlling for cognitive abilities, the results revealed that children with spina bifida showed impaired route knowled...

BACKGROUND Population-based empirical information to inform health care professionals working with children with spina bifida currently is lacking. Spina bifida is a highly complex condition that not only affects mobility but many additional aspects of life. We have developed a pilot project that focuses on a broad range of domains: surgeries, development and learning, nutrition and physical gr...

This communication continues the analysis of data accumulated from a series of cases of spina bifida cystica observed during the years 1949 to 1958. In earlier papers, attention was drawn to the magnitude of the problem presented by these cases and to the amount of medical and surgical care which they require (Doran and Guthkelch, 1961) and to certain complications which need consideration in p...

Spina bifida is one of the most common neural tube defects (NTDs) with a complex etiology. Variants in planar cell polarity (PCP) genes have been associated with NTDs including spina bifida in both animal models and human cohorts. In this study, we sequenced all exons of CELSR1 in 192 spina bifida patients from a California population to determine the contribution of CELSR1 mutations in the stu...

Spina bifida is among the phenotypes of the larger condition known as neural tube defects (NTDs). It is the most common central nervous system malformation compatible with life and the second leading cause of birth defects after congenital heart defects. In this review paper, we define spina bifida and discuss the phenotypes seen in humans as described by both surgeons and embryologists in orde...