Two new multi-component molecular complexes of cytosine and 5-fluorocytosine with 4-chloro-3,5-dinitrobenzoic acid are presented. Materials synthesis was achieved initially by evaporative crystallisation and the crystal structures determined. The process was then successfully transferred into a controlled small scale cooling crystallisation environment, with bulk samples shown to be representat...

Ice nucleation is a stochastic process and it is very difficult to be controlled. Freezing technologies and more specifically crystallisation assisted by magnetic, electric and electromagnetic fields have the capability to interact with nucleation. Static magnetic field (SMF) may affect matter crystallisation; however, this is still under debate in the literature. Static electric field (SEF) ha...

Numerous biliary proteins as well as non-protein factors influence kinetics of cholesterol crystallisation from supersaturated bile. Cholesterol crystallisation pathways, methods used for quantitative evaluation of liquid-to-solid transition of cholesterol in bile and the classical concept of nucleation defect in pathogenesis of gallstones are reviewed in the first part of this article. The rel...

The first time-resolved in situ X-ray diffraction studies of the hydrothermal crystallisation of open-framework zinc phosphates reveal a pathway of sequential crystallisation involving formation of a metastable low dimensional chain phase before the growth of three-dimensional zeolitic architectures.

Wax crystallisation and deposition from offshore reservoirs have been causing serious problems such as plugged pipelines and reduced production flow rates. This issue is receiving more attention from the researchers and for commercial applications due to the shift in trend from using offshore production facilities to pipelines utilization. The aim of this study is the implementation of the Avra...

As synchrotron radiation becomes more intense, detectors become faster and structure-solving software becomes more elaborate, obtaining single crystals suitable for data collection is now the bottleneck in macromolecular crystallography. Hence, there is a need for novel and advanced crystallisation agents with the ability to crystallise proteins that are otherwise challenging. Here, an Anderson...

BACKGROUND Cholesterol gall stones are a frequent disease for which at present surgery is the usual therapy. Despite the importance of bile acids it has become evident that phospholipids are the main cholesterol solubilisers in bile. Even phospholipid components, such as fatty acids, have anticrystallising activity. AIM To synthesise fatty acid bile acid conjugates (FABACs) and study their ef...

The present study continues the research efforts of recent years on the 1 Faculty of Foundry Engineering, AGH University of Science and Technology, 23 Reymonta Street, 30-059, Kraków, Poland 2 School of Materials, The University of Manchester, Grosvenor Street, Manchester, M1 7HS, UK 3 Polish Academy of Sciences, 25 Reymonta Street, 30-059, Kraków, Poland Crystallisation curves Regarding the cr...

D. Quigley (Theory Group) The rates at which crystals nucleate and grow from either a supercooled melt, or a supersaturated solution, are essential inputs for solidification models in a variety of contexts. These include materials synthesis and processing, development of antifreeze strategies for cryopreservation, and understanding the formation of harmful biological crystals such as kidney st...