Fluidized bed agglomeration is an advanced technology to produce spherical coarse-grained material of uniform size ready for sale without any need for post-treatment. This study discusses the possibilities and appropriateness of an intelligent control method such as a fuzzy logic controller in simulating and controlling fluidized bed agglomeration performance. Modeling and simulation was perfor...

Spherical crystallization is a novel particle engineering/design technique developed by Kawashima et al, to overcome the problems associated with direct compression. Basically, it's single step process used for size enlargement of single, two or more, small dose or large dose drugs, in combination with or without diluent. The process of spherical crystallization involves simultaneous crystalliz...

Synthesis of widespread types of nanoparticles including metal oxides by plant extract is considered as alternative chemical synthesis methods. ZnO nanoparticles are synthesized by a biological process using flaxseeds (Linum usitatissimum L.) extract. The biosynthesized ZnO NPs were characterized by XRD and SEM, EDX, DLS spectroscopy. According to the SEM images, the synthesized nanopa...

In this paper, the results of the Spherical Oil Agglomeration of Abstract .45 micrometer superpits low grade co al pa rticles (Bagworth Colliery, U.K.) within a su spension are prese nte d.Demineralized agglomerates were recovered directly by sieving on a 106 micrometer sieve. Verygood reductions in the ash content of the feed coal samples were achieved. In order to reducethe high levels of the...

In the production of tablets, direct compression method is mostly used. comparison to traditional wet granulation approach, this cannot be used with sensitive pharmaceuticals and also has a lot more processing limitations. Spherical agglomeration novel for creating pharmaceutical dosage forms that are immediately compressible, process spherical agglomeration, which improves powder's qualities s...

A target of best dissolution improvement of poorly soluble drugs is a necessity for the success of formulation in industry. The present work describes the preparation, optimization, and evaluation of a new spherical agglomeration technique for glimepiride as a model of poorly soluble drugs. It involved the emulsification of a drug solution containing a dispersed carrier that tailors the crystal...