INTRODUCTION The nicotinamide adenine dinucleotide phosphate (NADPH)-dependent membrane protein 5alpha-reductase irreversibly catalyses the conversion of testosterone to the most potent androgen, 5alpha-dihydrotestosterone (DHT). In humans, two 5alpha-reductase isoenyzmes are expressed: type I and type II. Type II is found primarily in prostate tissue. Saw palmetto extract (SPE) has been widely...

Objectives Brain perfusion SPECT has been widely used for evaluation of brain perfusion and metabolic status. We aimed to compare different quantitative methods on Tc-99m-HMPAO SPET based on visual evaluation. Materials and Methods: Forty-seven patients were enrolled in this comparative study. Tc-99m-HMPAO brain SPET was performed. For semiquantitative analysis, two orbitomeatal (OM) composite ...

This article substantially advances upon state-of-the-art to enhance liver vessels segmentation accuracy by leveraging advantages of synthetic PET-CT (SPET-CT) images in addition computed tomography angiography (CTA) volumes. Our setup makes a hybrid solution modified generative adversarial network-convolutional autoencoder (GAN-cAED) combining ability GAN deliver SPET-CT with cAED network term...

Whole-body and single photon emission tomography (SPET) images during sodium iodide-131 (Na131I) ablation are useful to confirm the efficacy of ablation using 131I imaging. However, there have been no attempts to improve the quality of 131I imaging. We therefore investigated imaging protocols for 131I imaging in differentiated thyroid cancer (DTC). Phantoms containing 131I were used to simulate...

Autosomal dominant familial Parkinson’s disease (PD) due to the ·-synuclein (G209A) mutation shares similar clinical characteristics with sporadic PD. Pathological studies however indicate more widespread neuronal degeneration in the familial form. We performed 123I-FP-CIT SPET (DaTSCAN) study in nine patients with familial PD carrying the ·-synuclein (G209A) mutation and fifteen matched patien...

OBJECTIVE Evaluation of regional lung function is valuable prior to lung surgery in patients with chronic lung disease. Our aim was to evaluate the reproducibility of a locally developed single photon emission tomography/computed tomography (SPET/CT) programme between and within three observers in assessing lobar pulmonary volumes, perfusion and ventilation. SUBJECTS AND METHODS Twelve lung t...

The effects of an aqueous extract of the plant Scoparia dulcis (200 mg/kg) on the polyol pathway and lipid peroxidation were examined in the liver of streptozotocin adult diabetic male albino Wistar rats. The diabetic control rats (N = 6) presented a significant increase in blood glucose, sorbitol dehydrogenase, glycosylated hemoglobin and lipid peroxidation markers such as thiobarbituric acid ...

Technological advancement in hardware and software development in myocardial perfusion imaging (MPI) leads to the shortening of acquisition time and reduction of the radiation burden to patients. We compared semiquantitative perfusion results and functional parameters of the left ventricle between new dedicated cardiac system with astigmatic collimators called IQ-SPECT (Siemens Medical Solution...

Introduction. Early signs of response after applying wafers of carmustine-loaded polymers (gliadel) are difficult to assess with imaging because of time-related imaging changes. (99m)Tc-sestamibi (MIBI) brain single-photon emission tomography (SPET) has reportedly been used to reveal areas of cellularity distinguishing recurrent neoplasm from radionecrosis. Our aim was to explore the role of MI...

To the Editor: Although diagnostic radioiodine scintigraphy or single photon emission tomography/computed tomography (SPET/CT) have been widely used in the evaluation of recurrence in thyroidectomized differentiated thyroid cancer patients, these techniques have not been generally recommended for this purpose or for biopsy purposes, especially in low-risk patients [1-4]. In addition, normal rad...