interleukin-4 (il-4) is produced by t-helper cells type 2 (th2) and induces ige synthesis. t-helper cells type 1 (th1) produce interferon-gamma (ifn-gamma) which suppresses th2 and reduces il-4 induced ige production. in this :;tudy , we demonstrated that the levels of specific ige in the serum of atopic children (n=20) were elevated while il-4 production was increased and ifn-gamma secretion w...

background: the effect of nutrition in the course of multiple sclerosis (ms) is a topic of great interest. the present study was aimed to evaluate the immunoglobin e (ige) against egg and fish in ms patients compared to healthy controls. methods: between march 2012 and july 2012, 48 ms patients were selected and compared with 48 healthy subjects to assess the frequency of ige against egg and fi...

cow's milk allergy (cma) is an immunological response to cow's milk proteins such as casein, α-lactalbumin and β lactoglobulin. the aim of this study was to determine the most common cow's milk allergenic proteins in patients with cma and identify the most effective proteins in different allergic symptoms. eighty seven patients (≤18 years) with allergy to cow’s milk from 2006 to 2013 entered th...

serum ige assay is a mainstay step in the allergy work up. allergenic extracts and molecular components are available at present. this real life study compared the serum specific ige levels against allergenic extracts with allergenic molecules in patients allergic to parietaria, betulaceae , and mites. this retrospective real life study included 489 subjects with respiratory allergy. inclusion ...

The diagnosis of allergic diseases is based on a combination of clinical history, physical examination, in vivo challenges, and in vitro test methods for the detection of allergen-specific IgE antibodies in the serum of patients. In spite of the fact that the determination of allergen-specific IgE in serum is widely used in daily clinical practice, one should be aware that such determinations, ...