Conformational investigations have been carried out on derivatives of lysozyme in which tyrosines 20 and 23 were nitrated (NTa-lysozyme), or in which the nitrotyrosine residues had been reduced to aminotyrosine (ATn-lysozyme). Also, a derivative modified at the 6 tryptophan residues by reaction with 2-nitrophenyl sulfenyl chloride (NPSe-lysozyme) was studied. In optical rotatory dispersion meas...

In this paper, a decoding method incorporating word-level conndence measures for improved speech recognition is presented. At rst, we focus on the estimation of conndence measures from the word graph and evaluate them in word graph rescoring (2nd-pass in 2-pass search system). Next, we propose the lexical tree search (1st-pass in 2-pass search system) incorporating the word-level conndence meas...

In this paper we estimate the effect of income and wage rates on the labor supply of men and women, ages 20-24. Economic theory predicts a positive substitution effect and; providing leisure is a normal good, a negative income effect. In general, we do find such effects empirically. The magnitude of the results depends very heavily on whether or not we control for the young person's school stat...

Titrations and spectral measurements of sperm whale metmyoglobin (2) and apomyoglobin (3) in the presence of cupric ion indicate that the metal ion may form chelates with imidazole groups and some other proton-bearing groups such as peptide amides. The titration and spectral properties of complexes of certain histidine-containing peptides have proved to be similar to those of the protein (4). A...

Recent and ongoing developments in time-resolved spectroscopy have made it possible to monitor circular dichroism, magnetic circular dichroism, optical rotatory dispersion, and magnetic optical rotatory dispersion with nanosecond time resolution. These techniques have been applied to determine structural changes associated with the function of several proteins as well as to determine the nature...

We applied a methodology capable of resolving the optical rotatory power into atomic contributions. The individual atomic contributions to the optical rotatory power and molecular chirality of the methylhydroperoxide are obtained via a canonical transformation of the Hamiltonian by which the electric dipolar moment operator is transformed to the acceleration gauge formalism and the magnetic dip...