Potassium channels are trans-membrane proteins, which selectively transport K+ ions across cell membranes and play a key role in regulating the physiology of excitability cells and signal transduction pathways. Bothutous Schach (BS) scorpion venom consists of several polypeptides that could modulate ion channels. In this study, the effects of BS crude venom on passive and active electrophysiolo...

The activity of the magnocellular neurons (MCNs) of supraoptic nucleus (SON) is regulated by a variety of excitatory and inhibitory inputs. Opioids are one of the important compounds that affect these inputs at SON synapses. In this study, whole-cell patch clamp recording of SON neurons was used to investigate the effect of acute and repeated morphine administration on spontaneous inhibitory an...

the comparison between the views of ibne malek, in alfye, and his son, ibn al-nazem, in sharh ibn al-nazem ‘ala alfiye ibn malek, is one of the most important morphological and grammatical issues in the arabic grammer. alfye (ألفیة ابن مالک) is an educational poetry in arabic grammar that has been versed by ibne malek in the 13th century. at least 43 explanations have been written on this work....

This is the story of how a conventional middle-class American household?a surgeon, his wife and three normal children?had first to recognise, then to cope with and, finally, to exclude, an abnormal family member. Tony was a beautiful child, the eldest, and apart from long hours of screaming for no apparent reason, he seemed a normal baby. His intellectual and motor development was average, but ...

The natural environment is in a state of constant flux and living organisms are perpetually challenged to adapt to these changes. Yet the mechanisms of adaptation, which lead to the development of new characteristics or behaviours, have troubled philosophers and scientists since the days of ancient Greece. In fact, it was not until 1859, when Charles Darwin (1809– 1882) published The Origin of ...

LYDIE BOULLE, M.D. GRMEK, CATHERINE LUPOVICI, and JANINE SAMIONCONTET, Laennec. Catalogue des manuscrits scientifiques, Paris, Masson, 1982, 4to, pp. vi, 316, Fr. 200.00. The scientific manuscripts of Laennec, among them such important unpublished items as his course in the College de France embracing all of medicine, or a book on pathological anatomy, are now distributed in five libraries in t...

introduction dilated cardiomyopathy (dcm) is the leading cause of heart failure and arrhythmia. case presentation a 47-year-old male, diagnosed with dilated cardiomyopathy, died due to heart failure. during the screening of his family members, his 17-year-old daughter and 9-year-old son also had dilated cardiomyopathy. another daughter had died suddenly at the age of 12 years. conclusions we he...