In this study five marketed brands of aceclofenac 100 mg tablets have been evaluated using dissolution test in two different media with the aim to assess bioequivalence and to select a proper dissolution medium. Other general quality parameters of these tablets like weight variation, hardness, friability, disintegration time were also determined according to established protocols. All the brand...

Moisturizers are used for the treatment of dry and irritated skin. The benefit of moisturizers when used on normal skin has recently been challenged, since an earlier study indicated that the increased hydration that follows long-term use of moisturizers on normal skin may facilitate penetration of irritants. The aim of the present study was to evaluate short-term use of 2 different moisturizer...

Nisoldipine is poorly soluble drug. There is no official dissolution method available in the literature or recommended by regulatory agencies. In present study dissolution method was developed. the media selection was done by solubility study of drug in different pH as well as in different surfactant solution. Volume of media was found by calculating sink condition. Sodium lauryl suphate, 1.0% ...

Summary: Low frequency ultrasound in combination with Sodium Lauryl Sulphate (SLS), a known transdermal chemical enhancer has been found to enhance delivery of molecules through the skin. In this abstract, we report the effects of changing SLS concentration on cavitation, protein permeation through the skin and skin damage. Introduction: Low-frequency ultrasound (US), applied to skin via a liqu...

In this paper, nanostructured semiconductor PbS metal-chalcogenide thin films were fabricated by the chemical bath deposition method in a surface active agent environment. The structural, morphological, and optical properties of characterized X-ray diffraction, scanning electron microscopy, probe microscope ultraviolet-visible spectroscopy analyses. These analyses reveal that surfactant sodium ...

OBJECTIVES To evaluate the effect of three calcium sodium phosphosilicate (CSPS)/sodium monofluorophosphate containing dentifrices, compared to positive and negative controls on plaque re-growth in a non-brushing model, after 4 days of twice daily use, as determined by plaque area and Turesky plaque index (TPI). METHODS This was an exploratory, single-centre, examiner-blind, randomised, contr...

Curcumin is a phytoconstituent with wide range of biological activity. It is poorly soluble in water. In the present study a new dissolution medium was developed, as there is no validated dissolution method available in the literature. The composition of the dissolution medium was selected on the basis of solubility data at 37 degrees . Solubility data revealed that addition of surfactant may b...

In this work, the dissolution-absorption studies were conducted on marketed tablets of acyclovir (ACIVIR-200mg) and the mucoadhesive tablets of acyclovir using varying concentration of sodium lauryl sulfate as a permeation enhancer. The purpose of this study was to improve the absorption of acyclovir using sodium lauryl sulfate as permeation enhancer. The everted and perfused intestine model wa...