نتایج جستجو برای: sodium iodide 131
تعداد نتایج: 214912 فیلتر نتایج به سال:
Iodide uptake across the membranes of thyroid follicular cells and cancer cells occurs through an active transport process mediated by the sodium-iodide symporter (NIS). The rat and human NIS-coding genes were cloned and identified in 1996. Evaluation of NIS gene and protein expression is critical for the management of thyroid cancer, and several approaches to increase NIS levels have been trie...
III " Everything is possible but the impossible – just do it " 131 I is widely used clinically in the treatment of Graves´disease and differentiated thyroid cancer. However, cellular and molecular effects of 131 I irradiation in relation to absorbed dose are poorly documented. For instance, it is unknown what absorbed doses give rise to acute or delayed lethality, DNA damage that is fully resto...
Authors: Edward B. Silberstein, MD (University of Cincinnati Hospital, Cincinnati, OH); Abass Alavi, MD (Hospital of the University of Pennsylvania, Philadelphia, PA); Helena R. Balon, MD (William Beaumont Hospital, Royal Oak, MI); David V. Becker, MD (New York Hospital–Cornell Medical Center, New York, NY); David R. Brill, MD (Chambersburg Hospital, Chambersburg, PA); Susan E. M. Clarke, MD (G...
OBJECTIVE The aim of this study was to determine whether or not the titre of thyroid-stimulating hormone receptor antibody with stimulating (TRAb-S) activity changes in patients with Graves' disease (GD) or toxic multinodular goitres (TMNG) 3 months after treatment with sodium iodide ((131)I). SUBJECTS AND METHODS Serum specimens were obtained from 21 hyperthyroid patients (15 with GD and 6 w...
Molecular imaging, defined as the visual representation, characterization and quantification of biological processes at the cellular and subcellular levels within intact living organisms, can be obtained by various imaging technologies, including nuclear imaging methods. Imaging of normal thyroid tissue and differentiated thyroid cancer, and treatment of thyroid cancer with radioiodine rely on ...
UNLABELLED The tumor-homing property of mesenchymal stem cells (MSCs) allows targeted delivery of therapeutic genes into the tumor microenvironment. The application of sodium iodide symporter (NIS) as a theranostic gene allows noninvasive imaging of MSC biodistribution and transgene expression before therapeutic radioiodine application. We have previously shown that linking therapeutic transgen...
Radioactive iodide ((131)I-) protection studies have focused primarily on the thyroid gland and disturbances in the hypothalamic-pituitary-thyroid axis. The objective of the current study was to establish (131)I- urinary excretion profiles for saline, and the thyroid protectants, potassium iodide (KI) and ammonium perchlorate over a 75 hour time-course. Rats were administered (131)I- and 3 hour...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید