health care impact. This review focuses on factors contributing to sinusitis pathogenesis and chronicity, including anatomic factors, disturbances in mucociliary clearance, microbial pathogens, and inflammatory factors. A distinction is made between “infectious” and “noninfectious” types of inflammation in chronic sinusitis. The inflammatory characteristics of noninfectious inflammation are rev...

The authors describe a prospective pilot study designed to investigate the use of topical nasal antifungal spray in addition to systemic steroids and itraconazole in the treatment of allergic fungal sinusitis. Sixteen patients with a history of allergic fungal sinusitis were given fluconazole nasal spray and followed for 3 months. Stabilization or improvement of disease without significant side...

Allergic fungal sinusitis (AFS) has been recognized as an important cause of chronic sinusitis commonly caused by Aspergillus spp. and various dematiaceous fungi like Bipolaris, Alternaria, Curvalaria, and etc. Ulocladium botrytis is a non pathogenic environmental dematiaceous fungi, which has been recently described as a human pathogen. Ulocladium has never been associated with allergic fungal...

background: acute fulminant fungal sinusitis is a rapidly progressive disease with high mortality (50-80%) and occurring with increasing frequency in patients with acute leukemia. the purpose of the present study was early diagnosis of this le­thal infection. methods: in a cross-sectional study, 142 patients with hematological malignancies were studied immediately by initiation of chemotherapy ...

BACKGROUND Fungal rhino sinusitis (FRS) is an important infection of para nasal sinuses, which encompasses two main categories; invasive and noninvasive forms according to histopathological findings. Aspergillus spp are the most common species isolated from noninvasive form, while Mucorales are more frequently isolates from acute infections. METHODS Four hundred fifty patients suspected to fu...

Purpose of the study Chronic invasive fungal sinusitis is a rare condition, and the conventional treatment surgical debridement and systemic antifungal therapy such as amphotericin B. Recently, voriconazole has demonstrated superior efficacy in the treatment of invasive aspergillosis, compared to amphotericin B. However, its use in invasive fungal sinusitis in an HIV patient has not been reported.

Acute invasive fungal sinusitis is the most aggressive form of fungal sinusitis and can be fatal, especially in patients who are immunosuppressed. Early diagnosis and intervention are crucial and potentially lifesaving, so primary care providers must maintain a high index of suspicion for this disease. Patients may need to be admitted to the hospital for IV antifungal therapy and surgical debri...

Allergic fungal sinusitis (AFS) has been clinicopathologically defined as a noninvasive form of fungal infection. This study was designed to distinguish AFS among patients with chronic sinusitis who failed to respond to repeated courses of antibiotics and were therefore candidates for functional endoscopic sinus surgery (FESS) in Sari. Allergic mucin and sinus lavage was collected during F...

conclusion prompt diagnosis and treatment of isolated sphenoidal sinusitis is of utmost importance since it has noncharacteristic manifestations. noninvasive fungal sphenoidal sinusitis is best treated with sphenoidotomy. it seemed that abducens nerve palsy was associated with total sinus obstruction since patient condition improved promptly following the sphenoidotomy. background fungal sinusi...