Pancreatoduodenectomy is the treatment of choice for patients with benign and malignant disease of pancreatic head. Classic pancreatoduodenectomy was described by Whipple originally and included distal hemigastrectomy. Pylorus-preserving pancreatoduodenectomy (pylorus-preserving) was popularized in the late 1970s for benign disease and it included full preservation of the pylorus. However, dela...

Mycotic abdominal aortic aneurysms (MAAAs) are rare but often lethal with little data to guide management decisions. Given the paucity of on MAAAs, this study’s objective was describe a single tertiary center experience MAAAs focus presenting symptoms, causative organisms, and postoperative outcomes. This single-center retrospective study from June 2012 February 2020 all confirmed or strongly s...

BackgroundAberrations in the coagulation system have been implicated pathogenesis of interstitial lung disease (ILD). Anticoagulants proposed as a potential therapy ILD; however, randomized controlled trial examining warfarin treatment for IPF was terminated early due to increased death rates. This has led some speculate that specifically may be harmful ILD, and use direct oral anticoagulants (...

Chronic pruritus (CP) has considerable implications for QOL. However, its impact on health-related QOL and economic burden is not fully characterized. We administered a cross-sectional survey 132 patients with CP using the Health Utilities Index Mark 3 instrument. Normative data from healthy adults (n = 4,187) were obtained Joint Canada/US Survey of Health. Quality-adjusted life-year loss costs...

Immune checkpoint inhibitors and targeted therapies have profoundly altered the management of several cancers over past decade. Metastatic melanoma has been at forefront these changes. We provide here a nationwide overview an assessment changes in survival France. included 10,936 patients receiving systemic treatment for metastatic cutaneous between 2010 2017 using French National Health Insura...