The viability of the probiotic strain Lactobacillus plantarum subsp. plantarum, after its passage through simulated gastric and pancreatic juices, was evaluated as function of its pre-growth in a medium containing the known prebiotics pectin or inulin, and was compared to glucose used as control. The presence of pectin or inulin did not markedly affect the growth (10.07 log10 colony forming uni...

Microplastics are prevalent in the environment and have a strong affinity to pollutants owing their large specific surface area hydrophobicity. Once ingested, microplastics transport into organisms. This study investigated bisphenol A (BPA) desorption behavior from three microplastic materials, namely, polystyrene (PS), polypropylene (PP), polyamide (PA), under simulated biological gastrointest...

· To learn the anatomy of the gastro-intestinal tract; · To learn the physiology of the gastro-intestinal tract especially with regard to nutrition; · To learn the consequences of critical illness on the function of the gastro-intestinal tract; · To learn the causes of disturbances in the balance between intestinal bacteria spp and their effects on the function of the bowel; · To learn the cons...

The present article describes the second part of a study investigating the effect of adding vegetables on the nutritional, physico-chemical, and oxidative properties of wheat bread, and specifically focuses on bread that does not contain oil as an added ingredient. Wheat flour breads fortified with freeze-dried carrot, tomato, beetroot or broccoli were developed and assessed for their nutrition...

In this study, 69 lactobacilli isolated from Tibetan Qula, a raw yak milk cheese, were screened for their potential use as probiotics. The isolates were tested in terms of: Their ability to survive at pH 2.0, pH 3.0, and in the presence of 0.3% bile salts; tolerance of simulated gastric and intestinal juices; antimicrobial activity; sensitivity against 11 specific antibiotics; and their cell su...

Gastro-intestinal stromal tumours are rarely found in the oesophagus and it is uncommon for these tumours to present with rupture. In this paper, we report a case where the tumour ruptured through the distal oesophagus. As a result, the patient underwent surgical tumour dissection. A histopathological examination of the tumour mass confirmed that it was a gastro-intestinal stromal tumour. In th...

Human organic anion-transporting polypeptide B (OATP-B; OATP2B1) is expressed in the human intestinal epithelial cells, and is suggested to be involved in the intestinal absorption of anionic drugs in vivo. Although citrus juices have been shown to inhibit the function of human OATP-A (OATP1A2), the effect of citrus juices on the OATP-B function remains unclear. In this study, we aimed to exami...

• To learn the anatomy of the gastro-intestinal tract; • To learn the physiology of the gastro-intestinal tract especially with regard to nutrition; • To learn the consequences of critical illness on the function of the gastro-intestinal tract; • To learn the causes of disturbances in the balance between intestinal bacteria and their effects on the function of the bowel; • To learn the conseque...

Ionic liquids (ILs) have been exploited to improve the absorption of poorly water-soluble drugs. Custom-made ILs solubilized very high quantities of the poorly water-soluble drugs, danazol and itraconazole, and maintained drug solubilization under simulated gastro-intestinal conditions. A danazol-containing self-emulsifying IL formulation gave rise to 4.3-fold higher exposure than the crystalli...

Gastro-intestinal stromal tumours are uncommon malignancies of the gastro-intestinal tract, accounting for only 0.2% of all gastro-intestinal malignancies, but are the most common of abdominal sarcomas. Classically, they have been considered amenable only to early stage surgical intervention. Recent advances in targeted cancer therapies have led to the development of effective non-surgical trea...