Scavenger receptor class B type I (SR-BI) is a high-density lipoprotein receptor that regulates cholesterol efflux from the peripheral tissues to the liver. SR-BI has been identified on astrocytes and vascular smooth muscle cells in Alzheimer's disease brain and has been shown to mediate adhesion of microglia to fibrillar amyloid-β (Aβ). Here we report that SR-BI mediates perivascular macrophag...

A previous study of strontium/calcium (Sr/Ca) ratios in Paranthropus suggested that it consumed more animal foods than was previously believed. However, that study looked at Sr/Ca in fossil bone, which is known to be highly susceptible to diagenesis. Enamel, in contrast, is resistant to post-mortem alteration making it a more appropriate material for Sr/Ca analysis of Plio-Pleistocene fossils. ...

The total variability based i-vector has become one of the most dominant approaches for speaker verification. In addition to this, recently the sparse representation (SR) based speaker verification approaches have also been proposed and are found to give comparable performance. In SR based approach, the dictionary used for sparse representation is either exemplar or learned from data using the ...

Macrophages express a number of proteins involved in sterol efflux pathways, including apolipoprotein E (apoE) and scavenger receptor class B type I (SR-BI). We have investigated a potential interaction between these two sterol efflux pathways in modulating overall macrophage sterol flux. We utilized an experimental system in which we increased expression of each of these proteins to a high phy...

The signal recognition particle and its receptor (SR) target nascent secretory proteins to the ER. SR is a heterodimeric ER membrane protein whose subunits, SR a and SR b , are both members of the GTPase superfamily. Here we characterize a 27-kD protein in Saccharomyces cerevisiae (encoded by SRP102 ) as a homologue of mammalian SR b . This notion is supported ( a ) by Srp102p’s sequence simila...

The risk-neutral process is modeled by a four parameter self-similar process of independent increments with a self-decomposable law for its unit time distribution. Six different processes in this general class are theoretically formulated and empirically investigated. We show that all six models are capable of adequately synthesizing European option prices across the spectrum of strikes and mat...

As an extension of chemical looping combustion, chemical looping steam reforming (CLSR) has been developed for H2 production. During CLSR, a steam reforming (SR) process occurs following the reduction of catalysts by the reforming feedstock itself (termed “auto-reduction”), as opposed to a separate, dedicated reducing agent like H2. This paper studied SR performances of four common bio-compound...

background and aims. the antioxidant and anti-inflammatory properties of propolis were studied. since saliva contains antioxidants and radiotherapy of the head and neck mainly affects the saliva, salivary antioxidant defensive mechanism is compromised with oxidative stress produced by radiation therapy. therefore, the aim of the present study was to investigate the effect of propolis on salivar...