Purpose: We aim to evaluate and compare the efficacy safety of Silodosin, Mirabegron, Tadalafil as a medical expulsive therapy (MET) for lower ureteric stones in adults. Material Methods: A total number 150 cases who had unilateral single stone between December 2021 August 2022 were incorporated this prospective randomized comparative study. The patients randomly divided into 3 equal groups. fi...

BACKGROUND Premature ejaculation (PE) is the most common sexual disorder in men and studies reported prevalence up to 30% (1, 2). PE is not a life-threatening medical condition but it influences the quality of life (QoL). OBJECTIVES The aim of this study was to compare the efficiency, and safety of alpha blocker drugs in the treatment of patients with premature ejaculation (PE). Additionally ...

OBJECTIVES To compare the efficacy of silodosin (8 mg) vs tamsulosin (0.4 mg), as a medical expulsive therapy, in the management of distal ureteric stones (DUS) in terms of stone clearance rate and stone expulsion time. PATIENTS AND METHODS A prospective randomised study was conducted on 115 patients, aged 21-55 years, who had unilateral DUS of ⩽10 mm. Patients were divided into two groups. G...

Benign Prostatic Hyperplasia (BPH) Is A Chronic Condition Often Associated With Lower Urinary Tract Symptoms (LUTS) (Urinary Frequency, Urgency, A Weak And Intermittent Stream, Needing To Strain, A Sense Of Incomplete Emptying And Nocturia[1]). The Severity Of BPH-Related Luts Appears To Depend, At Least in Part, On Smooth Muscle Tone in The Prostate And Bladder Neck, Which is Mediated By Α1aAd...

OBJECTIVE To evaluate the sexual side effects including ejaculation after silodosin treatment in potent men with regular sexual activity, as well as possible alterations in seminal vesicle volume. METHODS Sexually active patients aged ≥ 40 years with moderate to severe lower urinary tract symptoms were enrolled prospectively. International Prostate Symptom Score (IPSS) and Quality of Life (Qo...

OBJECTIVES We assessed the efficacy and safety of two α1-adrenoceptor antagonists, tamsulosin and silodosin, in the treatment of male lower urinary tract symptoms. METHODS Men aged 50 years or older who had a total International Prostate Symptom Score (IPSS) of 8 or higher were enrolled in this study. Forty-six patients were randomized into two groups. Twenty-three patients were initially pre...

BACKGROUND Patients with diabetes experience lower urinary tract symptoms. Cystopathy may evolve into underactive bladder (UAB), depending on the degree and duration of the symptoms. In the present study, we aimed to investigate the effects of silodosin, an alpha1A-adrenoceptor (AR) antagonist, on UAB in a rat model of diabetes mellitus (DM). METHODS Female Sprague-Dawley rats (6 weeks old) w...

correspondence: steven A Kaplan institute for Bladder and Prostate health, Weill cornell Medical college, cornell University, F9 West, Box 261, 525 east 68th street, new York, nY 10065, UsA Tel +1 212 746 4811 Fax +1 212 746 5329 email [email protected] Objective: The uroselective α-blocker silodosin significantly improved International Prostate Symptom Score (IPSS) in two 12-week, double...