Surface enhanced Raman scattering (SERS) is demonstrating a lot of potentials as a sensitive precious probe for chemical and bioanalitical applications. Since long time, the vibrational spectroscopy provides highly specific chemical information about DNA, RNA, viruses and molecules that makes both FTIR and Raman spectroscopies well suited for “fingerprint” detection in biomedical analysis. Howe...

We report the modular formulation of ciprofloxacin-based pure theranostic nanodrugs that display enhanced antibacterial activities, as well as aggregation-induced emission (AIE) enhancement that was successfully used to image bacteria. The drug derivatives, consisting of ciprofloxacin, a perfluoroaryl ring, and a phenyl ring linked by an amidine bond, were efficiently synthesized by a straightf...

The structure and dynamics of luminescent excitons in tetracene thin films and nanoaggregates are investigated using time-resolved spectroscopy and theoretical calculations. The orientation of tetracene's transition dipole moment along its short molecular axis leads to properties qualitatively different from those observed in aggregates of phenylene-vinylene and thiophene oligomers, despite sim...

Photophysical property changes of organic dye can be realized by controlling their aggregation state. These result in red/blue shift absorption/emission band, activation phosphorescence, or photothermal/photodynamic effect (generating heat ROS). Because self-assembly aqueous environment, the obtained nanoaggregates show great potential for optical diagnosis and therapy cancer. (Aggregate. 2021;...

The formation of a molecular aggregate in a confined, nanodimensioned region of space leads to what might be termed a ‘molecular nanoaggregate’. The present review deals with a theoretical formulation termed ‘aggregation-enhanced Raman scattering’ (AERS), and its use in discussion of relative Raman band intensities and selection rules for nanoaggregates. AERs represents a concept for discussion...

Asphaltenes are a group of exotic hydrocarbons found in bitumen and other forms heavy crude oil derivatives. These hydrocarbons, with elusive chemistry, give derivatives (CODs), such as bitumen, its characteristic properties. In they form stable aggregates by interacting molecules, called asphaltene aggregates. Attempts have been made to enhance nanoparticles, like graphene Such studies success...

Looking for new metal-based anticancer treatments, in recent years many ruthenium complexes have been proposed as effective and safe potential drugs. In this context we have recently developed a novel approach for the in vivo delivery of Ru(III) complexes, preparing stable ruthenium-based nucleolipidic nanoaggregates endowed with significant antiproliferative activity. Herein we describe the ce...