There is an increasing interest in detecting genes, or genomic regions, that have been targeted by natural selection. The interest stems from a basic desire to learn more about evolutionary processes in humans and other organisms, and from the realization that inferences regarding selection may provide important functional information. This review provides a nonmathematical description of the i...

Intramuscular fat (IMF) content is an important trait affecting the quality of pork. Two Duroc populations selected for IMF were used to identify signatures of selection associated with IMF. The effects of selection were analyzed between selected and control animals within each population using principal component analysis and FST using 60k SNPs. Moreover, extended haplotype homozygosity-based ...

The role of positive selection in human evolution remains controversial. On the one hand, scans for positive selection have identified hundreds of candidate loci, and the genome-wide patterns of polymorphism show signatures consistent with frequent positive selection. On the other hand, recent studies have argued that many of the candidate loci are false positives and that most genome-wide sign...

Intramuscular fat (IMF) content is an important trait affecting the quality of pork. Two Duroc populations, one under positive selection for IMF and the other selected for decreased backfat but under stabilizing selection for IMF, were used to identify signatures of selection associated with IMF using 60,000 single-nucleotide polymorphism data. The effects of selection were analyzed between 2 l...

In this paper, we propose an approach for automatic generation of novel intrusion signatures. This approach can be used in the signature-based Network Intrusion Detection Systems (NIDSs) and for the automation of the process of intrusion detection in these systems. In the proposed approach, first, by using several one-class classifiers, the profile of the normal network traffic is established. ...