A preliminary investigations was carried out to study the antibacterial activity of the water soluble extracts of five and ten years old barks of Eugenia Jambolana Lam. (fam. Myrtaceae) on dysentery and diarrhoea forming micro organisms. It was observed that the barks of young plants have a better inhibitory effect on micro - organisms like Salmonella viballerup, Shigella dysenteriae 10, Shigel...

Evidence is presented that a high level Shiga toxin-producing strain Shigella dysenteriae 60R adheres to and invades the epithelial cell lines Hct8 and Henle 407. The invasive phenotype of S. dysenteriae 60R differs in four ways from the heretofore studied invasive Shigella phenotypes. First, S. dysenteriae 60R lacks the virulence plasmid characteristic of other invasive Shigella spp. and enter...

OBJECTIVE To determine the clinical manifestations and outcome of shigellosis among children infected with different species of Shigella. METHODS We identified all patients <15 years infected with Shigella admitted to the icddr, b Dhaka hospital during one year. Study staff reviewed admission records and repeated the physical examinations and history of patients daily. RESULTS Of 792 childr...

BACKGROUND & OBJECTIVES Shigella dysenteriae is one of the most virulent pathogens causing bacillary dysentery and is responsible for high mortality in infants. To reduce the load of antibiotic therapy for treating shigellosis, this study was carried out to assess the ex vivo effect of novel probiotic lactobacilli, isolated from infant's stool samples, on killing S. dysenteriae type 1 residing ...

The study was conducted to determine the prevalence of Shigella species and their antimicrobial resistance patterns in eastern Nepal. Stool samples submitted to the diagnostic laboratory of B.P. Koirala Institute of Health Sciences, Nepal, during August 2000-July 2004, were cultured for Shigella species and were confirmed by biochemical and serological tests. Of 53 Shigella species isolated, Sh...

BACKGROUND AND OBJECTIVES Bacterial resistance to antibiotics has motivated the researchers to evaluate the novel anti-bacterial compounds such as some thiazole and imidazole derivatives. Thereby, in this work, we investigated the anti-bacterial effects of one new thiazole and two new imidazole derivatives on Bacillus cereus, Listeria monocytogenes, Escherichia coli, Salmonella typhimurium, Pro...

The synthetic medium for Shigella dysenteriae which has hitherto been known contains many amino acids and also niacin-amide, although the necessity of which remains obscure (5, 11,12) . We have been examining the process of the evolution of the bacterial nutrition (or the retroevolution), especially about the nitrogen source. It is the purpose of this paper to report the nutritional nitrogen so...

Shigella toxin inhibits polyuridylic acid-directed polymerization of phenylalanine in ribosome-enzyme systems obtained from Escherichia coli or from Shigella dysenteriae. The inhibition is the result of toxin acting on ribosomes to prevent polyuridylic acid attachment.

Epidemiological studies of shigellosis in Bangladesh have demonstrated that surface-water sources can act as foci of infection. Studies of laboratory microcosms have shown that shigellae become nonculturable but remain viable when exposed to environmental samples of water. The present study was carried out to detect viable but nonculturable Shigella dysenteriae 1 from laboratory microcosms by t...