leptin (lep), the expression product of the obese gene produced primarily in the adipose tissue, is related to feed intake, growth and lipid metabolism. the aim of this study was to study the possible association between polymorphism of the lep gene with growth and carcass traits among three iranian sheep breeds of the shal, zandi and zel varieties. a total of 180 purebred animals of the shal, ...

Leptin (LEP), the expression product of the obese gene produced primarily in the adipose tissue, is related to feed intake, growth and lipid metabolism. The aim of this study was to study the possible association between polymorphism of the LEP gene with growth and carcass traits among three Iranian sheep breeds of the Shal, Zandi and Zel varieties. A total of 180 purebred animals of the Shal, ...

Like rituximab, monoclonal antibodies reactive with human leukocyte antigen have potent antilymphoma activity. However, size limits their vascular and tissue penetration. To mimic monoclonal antibody binding, nanomolecules have been synthesized, shown specific for the beta subunit of HLA-DR10, and selective for cells expressing this protein. Selective high affinity ligands (SHALs) containing th...

In the present work the approach density matrix deformation earlier developed by the author to study a quantum theory of the Early Universe (Planck’s scales) is applied to study a quantum theory of black holes. On this basis the author investigates the information paradox problem, entropy of the black hole remainders after evaporation, and consistency with the holographic principle. The possibi...

Ion channel gene expression can vary substantially among neurons of a given type, even though neuron-type-specific firing properties remain stable and reproducible. The mechanisms that modulate ion channel gene expression and stabilize neural firing properties are unknown. In Drosophila, we demonstrate that loss of the Shal potassium channel induces the compensatory rebalancing of ion channel e...

Diversity in the expression of ion channel proteins among neurons allows a wide range of excitability, growth and functional regulation. Ether-a-go-go (EAG), a member of the voltage-gated K channels, was characterized by spontaneous firing in nerve terminals and enhanced neurotransmitter release. In situ whole-cell patch-clamp recordings performed from the somata of Drosophila larval thoracic a...

the fecundity in sheep has been much interested for producers due to its economical importance. growth differentiation factor 9 (gdf9) is an autosomal gene with over dominance effect for twosingle nucleotide polymorphisms(snps), which resulted in sterility in homozygote mutant ewes and additive effect for three snps, without showing sterility event. in the present study, dna was extracted from ...

Shal l2 is a knowledge-based machine translation system with a symmetric architecture. The grammar rules, mapping rules between syntactic and conceptual (semantic) representations, and transfer rules for conceptual paraphrasing are all bi-directional knowledge sources used by both a parser and a generator.