High temperature adversely affects normal development of male germ cells in mammals. Acute heat stress induces the formation of stress granules (SGs) in a set of male germ cells, and the SGs have been proposed to protect those cells from heat-induced apoptosis. DAZL, one of DAZ (Deleted in Azoospermia) family proteins, was shown to be an essential component of SGs, which is required for SG form...

this paper presents a novel salient pole synchronous generator i.e. permanentmagnet-assisted salient-pole synchronous generator (pma-sgs). due to saturationof conventional synchronous generators (sgs), permanent-magnet-assisted salientpolesynchronous generators (pma-sgs) are presented. pma-sgs are a new type ofsalient-pole synchronous machines with extra permanent magnets (pms) betweenthe adjac...

Stress granules (SGs) are large cytoplasmic ribonucleoprotein complexes that are assembled when cells are exposed to stress. SGs promote the survival of stressed cells by contributing to the reprogramming of protein expression as well as by blocking pro-apoptotic signaling cascades. These cytoprotective effects implicated SGs in the resistance of cancer cells to radiation and chemotherapy. We h...

The dynamics of the subgrid-scale (SGS) stress and scalar flux in the convective atmospheric surface layer are studied using field measurements from the Advection Horizontal Array Turbulence Study (AHATS). We extend the array technique previously used to evaluate the SGS velocity and temperature to include measurements of the fluctuating pressure, enabling separation of the resolvableand subgri...

Enhanced and immediate expression of cyclooxygenase-2 (COX-2) mRNA is observed in IL-1β-stimulated OA chondrocytes but the synthesis of protein found significantly delayed. Here we investigated the role of stress granules (SGs), ribonucleoprotein complexes that regulate mRNA translation, in the delayed translation of COX-2 mRNAs in IL-1β-stimulated OA chondrocytes. Stimulation of human chondroc...

We have developed a model of cutaneous leishmaniasis due to Leishmania major that seeks to mimic the natural conditions of infection. 1,000 metacyclic promastigotes were coinoculated with a salivary gland sonicate (SGS) obtained from a natural vector, Phlebotomus papatasii, into the ear dermis of naive mice or of mice preexposed to SGS. The studies reveal a dramatic exacerbating effect of SGS o...

BACKGROUND Melanocytes are present in both basal epidermis and hair follicles. Melanocyte stem cells have been found in hair follicle bulge. During embryogenesis, the outer cells of the bulge differentiate into the sebaceous gland (SG) and proliferate. OBJECTIVE To identify and determine the distribution and morphological characteristics of melanocytes in human SGs. METHODS A total of 171 b...

Before undergoing neuroexocytosis, secretory granules (SGs) are mobilized and tethered to the cortical actin network by an unknown mechanism. Using an SG pull-down assay and mass spectrometry, we found that myosin VI was recruited to SGs in a Ca(2+)-dependent manner. Interfering with myosin VI function in PC12 cells reduced the density of SGs near the plasma membrane without affecting their bio...

Based on deep imaging from the Advanced Camera for Surveys aboard the Hubble Space Telescope (HST), we present new evidence that stellar feedback created a ∼1 kpc supergiant H i shell (SGS) and triggered star formation (SF) around its rim in the M81 Group dwarf irregular galaxy IC 2574. Using photometry of the resolved stars from the HST images, we measure the star formation history of a region...

Stress granules (SGs) are cytoplasmic aggregates of stalled translational preinitiation complexes that accumulate during stress. GW bodies/processing bodies (PBs) are distinct cytoplasmic sites of mRNA degradation. In this study, we show that SGs and PBs are spatially, compositionally, and functionally linked. SGs and PBs are induced by stress, but SG assembly requires eIF2alpha phosphorylation...