1 Instituto de Ciencia de Materiales de Sevilla (ICMS), Spanish Research Council (CSIC) and University of Seville, Seville, Spain, 2 Smart Materials, Nanophysics, Fondazione Istituto Italiano di Tecnologia (IIT), Genova, Italy, 3 Drug Discovery and Development Department, Fondazione Istituto Italiano di Tecnologia (IIT), Genova, Italy, 4 Instituto de Hortofruticultura Subtropical y Mediterránea...

Flavanones constitute the majority of flavonoids in citrus fruits such as sweet (Citrus sinensis) and sour oranges (C. aurantium) and their near relatives—tangerines/mandarins (C. reticulata), tangors and tangelos. The relevant chemical analytic literature was searched, abstracted, documented, standardized, examined for quality, enumerated, and summarized in a database for these citrus flavanon...

A flexible model and efficient solution strategies for discrete location problems Alfredo Marín a, Stefan Nickel b,∗, Justo Puerto c, Sebastian Velten b a Universidad de Murcia, Departamento de Estadística e Investigación Operativa, 30100 Murcia, Spain b Saarland University, Faculty of Law and Economics, P.O. Box 15 11 50, 66041 Saarbrücken, Germany c University of Seville, Faculty of Mathemati...

NanoSpain2009 09-12 March, 2009 Zaragoza-Spain CHEMICAL SYNTHESIS AND FUNCTIONAL CHARACTERIZATION OF VASOACTIVE INTESTINAL PEPTIDE (VIP) SILVER-PROTECTED NANOPARTICLES David Pozo, Paula M Castillo, Rebecca Klippstein, Rafael Fernandez-Montesinos, Ana P Zaderenko CABIMER-Andalusian Centre for Molecular Biology and Regenerative Medicine (CSICUniversity of Seville-UPO-Junta de Andalucia), Americo ...

6 Common techniques to monitor the quality of fruit at the time of harvest and in storage typically rely on destructive methods to measure physical properties such as firmness and hydration. The complex, inhomogeneous composition of most fruit mean that non-destructive ultrasonic methods for quality evaluation of fruit has typically been unsuccessful. A novel ultrasound method was developed whi...

At first glance, some papers seemed to have addressedthe important topic of a real comparison of apples and oranges. Table 3 reveals the truth. This article, certain to become the classic in the field, clearly demonstrates that apples and oranges are not only comparable; indeed they are quite similar. The admonition “Let’s not compare apples with oranges” should be replaced immediately with a m...

BACKGROUND 6',7'-Dihydroxybergamottin is a furanocoumarin that inhibits CYP3A4 and is found in grapefruit juice and Seville orange juice. Grapefruit juice increases the oral bioavailability of many CYP3A4 substrates, including cyclosporine (INN, ciclosporin), but intestinal P-glycoprotein may be a more important determinant of cyclosporine availability. OBJECTIVES To evaluate the contribution...

1 Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, University College London, WC1N 3BG, London, UK 2 Department of Neurology, University of Ljubljana, 1000 Ljubljana, Slovenia 3 Unidad de Trastornos del Movimiento, Servicio de Neurologı́a y Neurofisiologı́a Clı́nica, Instituto de Biomedicina de Sevilla, Hospital Universitario Virgen del Rocı́o/CSIC/Universidad...

PURPOSE Several severe drug interactions have been reported when sildenafil, a potent drug for the treatment of erectile dysfunction, is co-administered with drugs or herbal remedies that inhibit cytochrome P450 (CYP) 3A4. This study evaluates the effects of two citrus fruit juices, lemon and Seville orange, on the pharmacokinetics of sildenafil in male healthy subjects following a single oral ...