Although information on efficacy and adverse drug reactions is lacking, ribavirin has been used empirically for the treatment of severe acute respiratory syndrome (SARS). We report common adverse events in 110 patients with suspected or probable SARS who were treated with ribavirin. Sixty-one percent of the patients had evidence of hemolytic anemia, and hypocalcemia and hypomagnesmia were repor...

The severe acute respiratory syndrome caused by COVID-19 is now a global catastrophic event. Currently thereis no approved drug or vaccine for the disease. Methylene blue (MB, oxidized form, blue color) has been used inmany different areas of clinical medicine, ranging from malaria to orthopedics. Leucomethylene Blue (reduced formof MB, colorless) may be applied for the treatm...

BACKGROUND Fingolimod (FTY) mediates bronchoconstriction by interacting with sphingosine-1-phosphate receptors. The majority of the reported adverse respiratory events occur during the first weeks of treatment. CASE PRESENTATION A 49-year-old woman developed a life-threatening asthma attack after 6 months of continuous FTY treatment. The adverse event required prolonged hospitalization, and t...

Acute respiratory failure caused by pulmonary tuberculosis is a rare event but with a high mortality even while receiving mechanical ventilatory support. We report the case of a young man with severe pulmonary tuberculosis refractory to conventional therapy who successfully overcame the critical period of his condition using noninvasive ventilation and immunoadjuvant therapy that included three...

ten, and contained information relevant for clinicians. Chapter 26, which covered positron emission tomography (PET), was surprisingly thin, especially given the robust amount of recently published information on PET in lung cancer diagnosis and staging. More information on PET technique, examples of PET/computed-tomography fusion images, and clinically-oriented recommendations (eg, when should...

objective a 4-month-old female with osteogenesis imperfecta (oi) type ii was admitted in picu of our center due to severe respiratory distress and fever with a diagnosis of severe pneumonia, and mechanical ventilation was initiated. due to severe hypotonia, ncv and emg were performed, and spinal muscular atrophy (sma) type i was diagnosed.