The serum ferritin concentration is a clinical parameter measured widely for the differential diagnosis of anemia. Its levels increase with elevations of tissue iron stores and with inflammation, but studies on cellular sources of serum ferritin as well as its subunit composition, degree of iron loading and glycosylation have given rise to conflicting results. To gain further understanding of s...

Background Transfusion-induced iron overload leads to many complications in patients with β-thalassemia major. This study aimed to compare the level of iron stored in the liver and heart measured by MRI T2 * with ferritin levels in these patients. Materials and Methods This study was done on 52 patients with β-thalassemia major aged 7 to 29 years. Serum ferritin level was checked and heart and ...

background: early childhood caries (ecc) is a virulent form of dental caries that can destroy the primary dentition of preschool children. the purpose of this study was to investigate a possible association between ecc with serum iron and serum ferritin levels. materials and methods: following the ethical approval, 204 children aged 24–71 months were recruited for a double-blind, randomized cro...

"Serum ferritin" presents a paradox, as the iron storage protein ferritin is not synthesised in serum yet is to be found there. Serum ferritin is also a well known inflammatory marker, but it is unclear whether serum ferritin reflects or causes inflammation, or whether it is involved in an inflammatory cycle. We argue here that serum ferritin arises from damaged cells, and is thus a marker of c...

background: hemorrhagic transformation (ht) of ischemic stroke (is) is a detrimental complication. this study investigated the association between serum ferritin level and ht in patients with massive is of middle cerebral artery.   methods: thirty patients with massive is of middle cerebral artery were enrolled in this prospective cohort study. they were divided into two groups based on the ser...

introduction : it has been reported that low serum ferritin level may increase risk factor of febrile convulsion. the aim of this study was to determine the level of serum ferritin in children with and without febrile convulsion. materials and methods : 40 children, 20 case with febrile convulsion and 20 healthy controls were studied.  case and control group were matched for age, sex and weight...

Ferritin is highly expressed in many cancer types. Although a few studies have reported an association between high serum ferritin levels and an increased risk of prostate cancer, the results are inconsistent. Therefore, we performed a large case-control study consisting of 2002 prostate cancer patients and 951 control patients with benign prostatic hyperplasia (BPH). We found that high ferriti...

BACKGROUND As women go through menopause, serum estrogen decreases and ferritin increases. Decreased serum estrogen is well known to cause detrimental effects on bone health; however, data on the associations of serum ferritin with BMD before and after menopause are still lacking. Therefore, this study aimed to investigate the association between serum ferritin levels and BMD in premenopausal a...

background: hemorrhagic transformation (ht) of ischemic stroke (is) is a detrimental complication. this study investigated the association between serum ferritin level and ht in patients with massive is of middle cerebral artery.   methods: thirty patients with massive is of middle cerebral artery were enrolled in this prospective cohort study. they were divided into two groups based on the ser...

Elevated serum ferritin levels without a corresponding increase in tissue iron storage have been observed in patients with certain cancers. Increased synthesis of ferritin by cancer cells has also been reported. In order to see whether similar phenomena occurred in patients with neuroblastoma, we have screened serum ferritin levels in 58 children with neuroblastoma by counterelectrophoresis usi...